1 HisKA#1
233-292 aa · 60 aa · 13.2% of protein
Raw token
HisKA:233:0.0000000000229:292:60:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIF28668_RS03935
Histidine kinase, Classic
Clostridioides difficile · GCF_003490105
ClassHKTypeClassicLength453 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003490105#CDIF28668_RS03935Stable P2CS identifier used across views.
GenomeGCF_003490105Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length453 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 453 aa (38.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa453 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
342-453 aa · 112 aa · 24.7% of protein
Raw token
HATPase_c:342:1.13e-22:453:112:109- Raw architecture: HisKA:233:0.0000000000229:292:60:64#HATPase_c:342:1.13e-22:453:112:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003490105::NZ_CP012309.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span786269-788322Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF28668_00768RefSeq proteinWP_074116225.1
Context group ID
GCF_003490105::NZ_CP012309.1::G00016Context members
CDIF28668_RS03930CDIF28668_RS03935
Partner locus tags
CDIF28668_RS03930CDIF28668_RS03935
Partner old locus tags
CDIF28668_00767CDIF28668_00768
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_074116225.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIF28668_RS03935Primary locus identifier stored in the genes table.
Old locus tagCDIF28668_00768Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012309.1Sequence record reported by the local genomic context database.
Genomic interval786 961-788 322 nt1 362 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span786 269-788 322 ntGCF_003490105::NZ_CP012309.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003490105::NZ_CP012309.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012309.1All displayed genes belong to this local TCS context.
Neighborhood span786 269-788 322 nt2 054 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
786 269 nt788 322 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDIF28668_RS03930GCF_003490105#CDIF28668_RS03930
RROmpR
786 269-786 964 nt · Forward (+)
CDIF28668_RS03935GCF_003490105#CDIF28668_RS03935
HKClassicCurrent focus
786 961-788 322 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003490105#CDIF28668_RS03935The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1928009
Simplified PFAM architecture for HKOC_1928009
PFAM domain coverage: 172 / 453 aa (38.0%)
1 aa453 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[232-292] | HATPase_c[342-452]
- Domain count: 2
- Matched identifier: HKOC_1928009
- Positioned domains: HisKA 232-292 ; HATPase_c 342-452
Cluster members and taxonomy
Representative gene: GCF_003490105#CDIF28668_RS03935
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003490105
AssemblyASM349010v1 · Complete Genomehaploid
Genome composition4 214 812 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key