1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000819:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIF29020_RS17540
Histidine kinase, Classic
Clostridioides difficile · GCF_003482165
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_003482165#CDIF29020_RS17540Stable P2CS identifier used across views.
GenomeGCF_003482165Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:4.65e-30:668:104:109- Raw architecture: HisKA:449:0.00000000819:514:66:64#HATPase_c:565:4.65e-30:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labeltriadGCF_003482165::NZ_CP012325.1::G00050
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span3725261-3728755Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF29020_03445RefSeq proteinWP_009906364.1
Context group ID
GCF_003482165::NZ_CP012325.1::G00050Context members
CDIF29020_RS17535CDIF29020_RS17540CDIF29020_RS17545
Partner locus tags
CDIF29020_RS17535CDIF29020_RS17540CDIF29020_RS17545
Partner old locus tags
CDIF29020_03444CDIF29020_03445CDIF29020_03446
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_009906364.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIF29020_RS17540Primary locus identifier stored in the genes table.
Old locus tagCDIF29020_03445Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012325.1Sequence record reported by the local genomic context database.
Genomic interval3 725 991-3 728 006 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 725 261-3 728 755 ntGCF_003482165::NZ_CP012325.1::G00050
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003482165::NZ_CP012325.1::G00050Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012325.1All displayed genes belong to this local TCS context.
Neighborhood span3 725 261-3 728 755 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 725 261 nt3 728 755 nt
Neighborhood gene cards
3 genes in the current local neighborhood.
CDIF29020_RS17535GCF_003482165#CDIF29020_RS17535
RROmpR
3 725 261-3 725 941 nt · Reverse (-)
CDIF29020_RS17540GCF_003482165#CDIF29020_RS17540
HKClassicCurrent focus
3 725 991-3 728 006 nt · Reverse (-)
CDIF29020_RS17545GCF_003482165#CDIF29020_RS17545
RROmpR
3 728 078-3 728 755 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0216030Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842458
Simplified PFAM architecture for HKOC_0842458
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842458
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0216030
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003482165
AssemblyASM348216v1 · Complete Genomehaploid
Genome composition4 139 418 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key