1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw token
HisKA:85:0.00000000000201:154:70:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIF28669_RS03585
Histidine kinase, Classic
Clostridioides difficile · GCF_003482125
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003482125#CDIF28669_RS03585Stable P2CS identifier used across views.
GenomeGCF_003482125Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw token
HATPase_c:201:3.45e-27:304:106:109- Raw architecture: HisKA:85:0.00000000000201:154:70:64#HATPase_c:201:3.45e-27:304:106:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003482125::NZ_CP012323.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span694133-695739Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF28669_00716RefSeq proteinWP_003427880.1
Context group ID
GCF_003482125::NZ_CP012323.1::G00011Context members
CDIF28669_RS03580CDIF28669_RS03585
Partner locus tags
CDIF28669_RS03580CDIF28669_RS03585
Partner old locus tags
CDIF28669_00715CDIF28669_00716
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003427880.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DAK6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DAK6_CLODIDisplay identifier provided by UniProt.
GO / PubMed1 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIF28669_RS03585Primary locus identifier stored in the genes table.
Old locus tagCDIF28669_00716Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012323.1Sequence record reported by the local genomic context database.
Genomic interval694 822-695 739 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span694 133-695 739 ntGCF_003482125::NZ_CP012323.1::G00011
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003482125::NZ_CP012323.1::G00011Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012323.1All displayed genes belong to this local TCS context.
Neighborhood span694 133-695 739 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
694 133 nt695 739 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDIF28669_RS03580GCF_003482125#CDIF28669_RS03580
RROmpR
694 133-694 822 nt · Forward (+)
CDIF28669_RS03585GCF_003482125#CDIF28669_RS03585
HKClassicCurrent focus
694 822-695 739 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS03460Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2882018
Simplified PFAM architecture for HKOC_2882018
PFAM domain coverage: 171 / 305 aa (56.1%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[88-154] | HATPase_c[201-304]
- Domain count: 2
- Matched identifier: HKOC_2882018
- Positioned domains: HisKA 88-154 ; HATPase_c 201-304
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS03460
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003482125
AssemblyASM348212v1 · Complete Genomehaploid
Genome composition4 137 693 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key