1 HisKA#1
308-374 aa · 67 aa · 12.7% of protein
Raw token
HisKA:308:0.0000000000000147:374:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIF28666_RS12240
Histidine kinase, Classic
Clostridioides difficile · GCF_003482065
ClassHKTypeClassicLength529 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003482065#CDIF28666_RS12240Stable P2CS identifier used across views.
GenomeGCF_003482065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length529 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 529 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa529 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
427-512 aa · 86 aa · 16.3% of protein
Raw token
HATPase_c:427:0.0000000417:512:90:109- Raw architecture: HisKA:308:0.0000000000000147:374:67:64#HATPase_c:427:0.0000000417:512:90:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003482065::NZ_CP012321.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2543298-2545572Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF28666_02413RefSeq proteinWP_021364639.1
Context group ID
GCF_003482065::NZ_CP012321.1::G00040Context members
CDIF28666_RS12235CDIF28666_RS12240
Partner locus tags
CDIF28666_RS12235CDIF28666_RS12240
Partner old locus tags
CDIF28666_02412CDIF28666_02413
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021364639.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RJK1Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RJK1_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIF28666_RS12240Primary locus identifier stored in the genes table.
Old locus tagCDIF28666_02413Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012321.1Sequence record reported by the local genomic context database.
Genomic interval2 543 983-2 545 572 nt1 590 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 543 298-2 545 572 ntGCF_003482065::NZ_CP012321.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003482065::NZ_CP012321.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012321.1All displayed genes belong to this local TCS context.
Neighborhood span2 543 298-2 545 572 nt2 275 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 543 298 nt2 545 572 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDIF28666_RS12235GCF_003482065#CDIF28666_RS12235
RROmpR
2 543 298-2 544 014 nt · Forward (+)
CDIF28666_RS12240GCF_003482065#CDIF28666_RS12240
HKClassicCurrent focus
2 543 983-2 545 572 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448745#QC1_RS12255Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1359831
Simplified PFAM architecture for HKOC_1359831
PFAM domain coverage: 191 / 529 aa (36.1%)
1 aa529 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[254-294] | HisKA[309-374] | HATPase_c[426-509]
- Domain count: 3
- Matched identifier: HKOC_1359831
- Positioned domains: HAMP 254-294 ; HisKA 309-374 ; HATPase_c 426-509
Cluster members and taxonomy
Representative gene: GCF_000448745#QC1_RS12255
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003482065
AssemblyASM348206v1 · Complete Genomehaploid
Genome composition4 122 585 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key