1 HAMP#1
4-56 aa · 53 aa · 17.4% of protein
Raw token
HAMP:4:0.0000187:56:53:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIF28666_RS01640
Histidine kinase, Classic
Clostridioides difficile · GCF_003482065
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003482065#CDIF28666_RS01640Stable P2CS identifier used across views.
GenomeGCF_003482065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage226 / 305 aa (74.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation3 items
2 HisKA#2
85-150 aa · 66 aa · 21.6% of protein
Raw token
HisKA:85:0.0000000906:150:66:643 HATPase_c#3
197-303 aa · 107 aa · 35.1% of protein
Raw token
HATPase_c:197:1.66e-30:303:107:109- Raw architecture: HAMP:4:0.0000187:56:53:69#HisKA:85:0.0000000906:150:66:64#HATPase_c:197:1.66e-30:303:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003482065::NZ_CP012321.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span277827-279443Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF28666_00332RefSeq proteinWP_070421136.1
Context group ID
GCF_003482065::NZ_CP012321.1::G00002Context members
CDIF28666_RS01640CDIF28666_RS01645
Partner locus tags
CDIF28666_RS01640CDIF28666_RS01645
Partner old locus tags
CDIF28666_00332CDIF28666_00333
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_070421136.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIF28666_RS01640Primary locus identifier stored in the genes table.
Old locus tagCDIF28666_00332Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012321.1Sequence record reported by the local genomic context database.
Genomic interval277 827-278 744 nt918 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span277 827-279 443 ntGCF_003482065::NZ_CP012321.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003482065::NZ_CP012321.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012321.1All displayed genes belong to this local TCS context.
Neighborhood span277 827-279 443 nt1 617 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
277 827 nt279 443 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDIF28666_RS01640GCF_003482065#CDIF28666_RS01640
HKClassicCurrent focus
277 827-278 744 nt · Reverse (-)
CDIF28666_RS01645GCF_003482065#CDIF28666_RS01645
RROmpR
278 751-279 443 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003482065#CDIF28666_RS01640The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2882373
Simplified PFAM architecture for HKOC_2882373
PFAM domain coverage: 169 / 305 aa (55.4%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[85-148] | HATPase_c[199-303]
- Domain count: 2
- Matched identifier: HKOC_2882373
- Positioned domains: HisKA 85-148 ; HATPase_c 199-303
Cluster members and taxonomy
Representative gene: GCF_003482065#CDIF28666_RS01640
Displayed with 5 columns and 10 rows per page from the local display config.
Showing members 1 to 6 over 6 total members. Page 1 / 1.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003482065
AssemblyASM348206v1 · Complete Genomehaploid
Genome composition4 122 585 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key