Gene detail

CDIF29632_RS10180

Histidine kinase, Classic

Clostridioides difficile · GCF_003481965

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003481965#CDIF29632_RS10180Stable P2CS identifier used across views.
GenomeGCF_003481965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827962Run 6 · 300 sequences · id 100% · cov 80%
External referencesWP_021363597.1 · MIST4 CDIF29632_RS10180RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for CDIF29632_RS10180
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.000000341:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:5.71e-24:341:101:109
  • Raw architecture: HisKA:124:0.000000341:189:66:64#HATPase_c:241:5.71e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003481965::NZ_CP019860.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2120112-2121819Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF29632_02010RefSeq proteinWP_021363597.1
Context group IDGCF_003481965::NZ_CP019860.1::G00035
Context members
CDIF29632_RS10175CDIF29632_RS10180
Partner locus tags
CDIF29632_RS10175CDIF29632_RS10180
Partner old locus tags
CDIF29632_02009CDIF29632_02010
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021363597.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF29632_RS10180Primary locus identifier stored in the genes table.
Old locus tagCDIF29632_02010Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP019860.1Sequence record reported by the local genomic context database.
Genomic interval2 120 788-2 121 819 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 120 112-2 121 819 ntGCF_003481965::NZ_CP019860.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003481965::NZ_CP019860.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP019860.1All displayed genes belong to this local TCS context.
Neighborhood span2 120 112-2 121 819 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 120 112 nt2 121 819 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF29632_RS10175GCF_003481965#CDIF29632_RS10175
RROmpR

2 120 112-2 120 798 nt · Forward (+)

Old locus CDIF29632_02009RefSeq WP_011861401.1
CDIF29632_RS10180GCF_003481965#CDIF29632_RS10180
HKClassicCurrent focus

2 120 788-2 121 819 nt · Forward (+)

Old locus CDIF29632_02010RefSeq WP_021363597.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827962Run 6 · HK · 300 sequences
Representative sequenceGCF_000448905#QAY_RS09450Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827962

Simplified PFAM architecture for HKOC_2827962

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827962
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448905#QAY_RS09450

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003481965
AssemblyASM348196v1 · Complete Genomehaploid
Genome composition4 175 826 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key