Gene detail

DWX32_RS00745

Histidine kinase, Classic

Blautia sp. AF19-13LB · GCF_003479105

ClassHKTypeClassicLength600 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003479105#DWX32_RS00745Stable P2CS identifier used across views.
GenomeGCF_003479105Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1053603Run 6 · 15 sequences · id 100% · cov 80%
External referencesWP_117760396.1 · MIST4 DWX32_RS00745RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length600 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage502 / 600 aa (83.7%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa600 aa
dCache_1: 41-288 aa (248 aa)1HAMP: 305-375 aa (71 aa)2His_kinase: 390-469 aa (80 aa)3HATPase_c: 488-590 aa (103 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
41-288 aa · 248 aa · 41.3% of protein
Raw tokendCache_1:41:0.000000183:288:253:195
2 HAMP#2
305-375 aa · 71 aa · 11.8% of protein
Raw tokenHAMP:305:0.00000000124:375:71:69
3 His_kinase#3
390-469 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:390:2.03e-27:469:80:80
4 HATPase_c#4
488-590 aa · 103 aa · 17.2% of protein
Raw tokenHATPase_c:488:0.0000000000963:590:109:109
  • Raw architecture: dCache_1:41:0.000000183:288:253:195#HAMP:305:0.00000000124:375:71:69#His_kinase:390:2.03e-27:469:80:80#HATPase_c:488:0.0000000000963:590:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003479105::NZ_QUGO01000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span133730-137046Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWX32_00745RefSeq proteinWP_117760396.1
Context group IDGCF_003479105::NZ_QUGO01000001.1::G00003
Context members
DWX32_RS00740DWX32_RS00745
Partner locus tags
DWX32_RS00740DWX32_RS00745
Partner old locus tags
DWX32_00740DWX32_00745
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117760396.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWX32_RS00745Primary locus identifier stored in the genes table.
Old locus tagDWX32_00745Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUGO01000001.1Sequence record reported by the local genomic context database.
Genomic interval135 244-137 046 nt1 803 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span133 730-137 046 ntGCF_003479105::NZ_QUGO01000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003479105::NZ_QUGO01000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUGO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span133 730-137 046 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
133 730 nt137 046 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWX32_RS00740GCF_003479105#DWX32_RS00740
RRunclassified

133 730-135 247 nt · Forward (+)

Old locus DWX32_00740RefSeq WP_118659121.1
DWX32_RS00745GCF_003479105#DWX32_RS00745
HKClassicCurrent focus

135 244-137 046 nt · Forward (+)

Old locus DWX32_00745RefSeq WP_117760396.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1053603Run 6 · HK · 15 sequences
Representative sequenceGCF_003462165#DW746_RS01440Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1053603

Simplified PFAM architecture for HKOC_1053603

PFAM domain coverage: 229 / 600 aa (38.2%)

1 aa600 aa
HAMP: 329-374 aaHAMPHis_kinase: 390-468 aaHis_kinaseHATPase_c: 487-590 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[329-374] | His_kinase[390-468] | HATPase_c[487-590]
  • Domain count: 3
  • Matched identifier: HKOC_1053603
  • Positioned domains: HAMP 329-374 ; His_kinase 390-468 ; HATPase_c 487-590
Cluster members and taxonomy
Visualization

Representative gene: GCF_003462165#DW746_RS01440

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 962 · GCF_003479105
AssemblyASM347910v1 · Scaffoldhaploid
Genome composition4 009 812 bp · 47,5% GCBlautia sp. AF19-13LB
Signal transduction countsGenes 99 · HK 49 · RR 47CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key