Gene detail

DWZ60_RS04540

Histidine kinase, Classic

Blautia sp. AF34-10 · GCF_003477865

ClassHKTypeClassicLength571 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003477865#DWZ60_RS04540Stable P2CS identifier used across views.
GenomeGCF_003477865Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1207821Run 6 · 9 sequences · id 100% · cov 80%
External referencesWP_055266927.1 · A0A174NED7 · MIST4 DWZ60_RS04540RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length571 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage260 / 571 aa (45.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa571 aa
HAMP: 271-346 aa (76 aa)1His_kinase: 361-439 aa (79 aa)2HATPase_c: 458-562 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
271-346 aa · 76 aa · 13.3% of protein
Raw tokenHAMP:271:0.0000000000123:346:76:69
2 His_kinase#2
361-439 aa · 79 aa · 13.8% of protein
Raw tokenHis_kinase:361:3.89e-23:439:80:80
3 HATPase_c#3
458-562 aa · 105 aa · 18.4% of protein
Raw tokenHATPase_c:458:0.000000112:562:107:109
  • Raw architecture: HAMP:271:0.0000000000123:346:76:69#His_kinase:361:3.89e-23:439:80:80#HATPase_c:458:0.000000112:562:107:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003477865::NZ_QUED01000005.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span81620-83904Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWZ60_04560RefSeq proteinWP_055266927.1
Context group IDGCF_003477865::NZ_QUED01000005.1::G00046
Context members
DWZ60_RS04535DWZ60_RS04540
Partner locus tags
DWZ60_RS04535DWZ60_RS04540
Partner old locus tags
DWZ60_04555DWZ60_04560
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055266927.1Primary protein accession used for annex mappings.
UniProt accessionA0A174NED7Primary UniProt accession resolved in the annex database.
UniProt IDA0A174NED7_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWZ60_RS04540Primary locus identifier stored in the genes table.
Old locus tagDWZ60_04560Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUED01000005.1Sequence record reported by the local genomic context database.
Genomic interval82 189-83 904 nt1 716 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span81 620-83 904 ntGCF_003477865::NZ_QUED01000005.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003477865::NZ_QUED01000005.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUED01000005.1All displayed genes belong to this local TCS context.
Neighborhood span81 620-83 904 nt2 285 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
81 620 nt83 904 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWZ60_RS04535GCF_003477865#DWZ60_RS04535
RRunclassified

81 620-82 153 nt · Reverse (-)

Old locus DWZ60_04555RefSeq WP_158576309.1
DWZ60_RS04540GCF_003477865#DWZ60_RS04540
HKClassicCurrent focus

82 189-83 904 nt · Reverse (-)

Old locus DWZ60_04560RefSeq WP_055266927.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1207821Run 6 · HK · 9 sequences
Representative sequenceGCF_001406335#ARA47_RS09920Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1207821

Simplified PFAM architecture for HKOC_1207821

PFAM domain coverage: 232 / 571 aa (40.6%)

1 aa571 aa
HAMP: 294-344 aaHAMPHis_kinase: 364-437 aaHis_kinaseHATPase_c: 457-563 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[294-344] | His_kinase[364-437] | HATPase_c[457-563]
  • Domain count: 3
  • Matched identifier: HKOC_1207821
  • Positioned domains: HAMP 294-344 ; His_kinase 364-437 ; HATPase_c 457-563
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406335#ARA47_RS09920

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 968 · GCF_003477865
AssemblyASM347786v1 · Contighaploid
Genome composition3 555 463 bp · 47,5% GCBlautia sp. AF34-10
Signal transduction countsGenes 87 · HK 42 · RR 42CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key