Gene detail

DWZ60_RS04130

Histidine kinase, Classic

Blautia sp. AF34-10 · GCF_003477865

ClassHKTypeClassicLength570 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003477865#DWZ60_RS04130Stable P2CS identifier used across views.
GenomeGCF_003477865Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1212941Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_119221281.1 · MIST4 DWZ60_RS04130RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length570 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage472 / 570 aa (82.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa570 aa
dCache_1: 41-257 aa (217 aa)1HAMP: 287-356 aa (70 aa)2His_kinase: 371-450 aa (80 aa)3HATPase_c: 464-568 aa (105 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
41-257 aa · 217 aa · 38.1% of protein
Raw tokendCache_1:41:0.00000002:257:219:195
2 HAMP#2
287-356 aa · 70 aa · 12.3% of protein
Raw tokenHAMP:287:0.000000000000119:356:70:69
3 His_kinase#3
371-450 aa · 80 aa · 14.0% of protein
Raw tokenHis_kinase:371:1.07e-29:450:80:80
4 HATPase_c#4
464-568 aa · 105 aa · 18.4% of protein
Raw tokenHATPase_c:464:2.14e-18:568:111:109
  • Raw architecture: dCache_1:41:0.00000002:257:219:195#HAMP:287:0.000000000000119:356:70:69#His_kinase:371:1.07e-29:450:80:80#HATPase_c:464:2.14e-18:568:111:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003477865::NZ_QUED01000004.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span180506-183692Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWZ60_04150RefSeq proteinWP_119221281.1
Context group IDGCF_003477865::NZ_QUED01000004.1::G00042
Context members
DWZ60_RS04130DWZ60_RS04135
Partner locus tags
DWZ60_RS04130DWZ60_RS04135
Partner old locus tags
DWZ60_04150DWZ60_04155
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_119221281.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWZ60_RS04130Primary locus identifier stored in the genes table.
Old locus tagDWZ60_04150Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUED01000004.1Sequence record reported by the local genomic context database.
Genomic interval180 506-182 218 nt1 713 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span180 506-183 692 ntGCF_003477865::NZ_QUED01000004.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003477865::NZ_QUED01000004.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUED01000004.1All displayed genes belong to this local TCS context.
Neighborhood span180 506-183 692 nt3 187 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
180 506 nt183 692 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWZ60_RS04130GCF_003477865#DWZ60_RS04130
HKClassicCurrent focus

180 506-182 218 nt · Reverse (-)

Old locus DWZ60_04150RefSeq WP_119221281.1
DWZ60_RS04135GCF_003477865#DWZ60_RS04135
RRunclassified

182 196-183 692 nt · Reverse (-)

Old locus DWZ60_04155RefSeq WP_119221282.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1212941Run 6 · HK · 1 sequences
Representative sequenceGCF_003477865#DWZ60_RS04130The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1212941

Simplified PFAM architecture for HKOC_1212941

PFAM domain coverage: 235 / 570 aa (41.2%)

1 aa570 aa
HAMP: 305-356 aaHAMPHis_kinase: 372-449 aaHis_kinaseHATPase_c: 465-569 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[305-356] | His_kinase[372-449] | HATPase_c[465-569]
  • Domain count: 3
  • Matched identifier: HKOC_1212941
  • Positioned domains: HAMP 305-356 ; His_kinase 372-449 ; HATPase_c 465-569
Cluster members and taxonomy
Visualization

Representative gene: GCF_003477865#DWZ60_RS04130

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 968 · GCF_003477865
AssemblyASM347786v1 · Contighaploid
Genome composition3 555 463 bp · 47,5% GCBlautia sp. AF34-10
Signal transduction countsGenes 87 · HK 42 · RR 42CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key