Gene detail

DWZ60_RS02860

Histidine kinase, Classic

Blautia sp. AF34-10 · GCF_003477865

ClassHKTypeClassicLength550 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003477865#DWZ60_RS02860Stable P2CS identifier used across views.
GenomeGCF_003477865Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1293114Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_117509490.1 · A0AAE3F064 · MIST4 DWZ60_RS02860RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length550 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage259 / 550 aa (47.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa550 aa
HAMP: 262-331 aa (70 aa)1His_kinase: 347-426 aa (80 aa)2HATPase_c: 437-545 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
262-331 aa · 70 aa · 12.7% of protein
Raw tokenHAMP:262:0.000000000000802:331:70:69
2 His_kinase#2
347-426 aa · 80 aa · 14.5% of protein
Raw tokenHis_kinase:347:2.79e-21:426:80:80
3 HATPase_c#3
437-545 aa · 109 aa · 19.8% of protein
Raw tokenHATPase_c:437:0.00000000019:545:114:109
  • Raw architecture: HAMP:262:0.000000000000802:331:70:69#His_kinase:347:2.79e-21:426:80:80#HATPase_c:437:0.00000000019:545:114:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003477865::NZ_QUED01000003.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span88164-90567Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWZ60_02880RefSeq proteinWP_117509490.1
Context group IDGCF_003477865::NZ_QUED01000003.1::G00032
Context members
DWZ60_RS02855DWZ60_RS02860
Partner locus tags
DWZ60_RS02855DWZ60_RS02860
Partner old locus tags
DWZ60_02875DWZ60_02880
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_117509490.1Primary protein accession used for annex mappings.
UniProt accessionA0AAE3F064Primary UniProt accession resolved in the annex database.
UniProt IDA0AAE3F064_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWZ60_RS02860Primary locus identifier stored in the genes table.
Old locus tagDWZ60_02880Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUED01000003.1Sequence record reported by the local genomic context database.
Genomic interval88 915-90 567 nt1 653 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span88 164-90 567 ntGCF_003477865::NZ_QUED01000003.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003477865::NZ_QUED01000003.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUED01000003.1All displayed genes belong to this local TCS context.
Neighborhood span88 164-90 567 nt2 404 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
88 164 nt90 567 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWZ60_RS02855GCF_003477865#DWZ60_RS02855
RRunclassified

88 164-88 898 nt · Reverse (-)

Old locus DWZ60_02875RefSeq WP_117509489.1
DWZ60_RS02860GCF_003477865#DWZ60_RS02860
HKClassicCurrent focus

88 915-90 567 nt · Reverse (-)

Old locus DWZ60_02880RefSeq WP_117509490.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1293114Run 6 · HK · 10 sequences
Representative sequenceGCF_003435675#DW642_RS05135Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1293114

Simplified PFAM architecture for HKOC_1293114

PFAM domain coverage: 236 / 550 aa (42.9%)

1 aa550 aa
HAMP: 282-331 aaHAMPHis_kinase: 348-425 aaHis_kinaseHATPase_c: 438-545 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[282-331] | His_kinase[348-425] | HATPase_c[438-545]
  • Domain count: 3
  • Matched identifier: HKOC_1293114
  • Positioned domains: HAMP 282-331 ; His_kinase 348-425 ; HATPase_c 438-545
Cluster members and taxonomy
Visualization

Representative gene: GCF_003435675#DW642_RS05135

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 968 · GCF_003477865
AssemblyASM347786v1 · Contighaploid
Genome composition3 555 463 bp · 47,5% GCBlautia sp. AF34-10
Signal transduction countsGenes 87 · HK 42 · RR 42CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key