Gene detail

DW085_RS12395

Histidine kinase, Classic

Clostridium sp. AF50-3 · GCF_003477445

ClassHKTypeClassicLength491 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003477445#DW085_RS12395Stable P2CS identifier used across views.
GenomeGCF_003477445Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1528565Run 6 · 25 sequences · id 100% · cov 80% · representative
External referencesWP_118492943.1 · MIST4 DW085_RS12395RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length491 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 491 aa (50.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa491 aa
HAMP: 182-251 aa (70 aa)1HisKA: 265-329 aa (65 aa)2HATPase_c: 376-486 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
182-251 aa · 70 aa · 14.3% of protein
Raw tokenHAMP:182:7.12e-17:251:70:69
2 HisKA#2
265-329 aa · 65 aa · 13.2% of protein
Raw tokenHisKA:265:9.32e-16:329:65:64
3 HATPase_c#3
376-486 aa · 111 aa · 22.6% of protein
Raw tokenHATPase_c:376:1.97e-30:486:111:109
  • Raw architecture: HAMP:182:7.12e-17:251:70:69#HisKA:265:9.32e-16:329:65:64#HATPase_c:376:1.97e-30:486:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003477445::NZ_QUDH01000010.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span134751-136965Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW085_12390RefSeq proteinWP_118492943.1
Context group IDGCF_003477445::NZ_QUDH01000010.1::G00005
Context members
DW085_RS12390DW085_RS12395
Partner locus tags
DW085_RS12390DW085_RS12395
Partner old locus tags
DW085_12385DW085_12390
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_118492943.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW085_RS12395Primary locus identifier stored in the genes table.
Old locus tagDW085_12390Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUDH01000010.1Sequence record reported by the local genomic context database.
Genomic interval135 490-136 965 nt1 476 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span134 751-136 965 ntGCF_003477445::NZ_QUDH01000010.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003477445::NZ_QUDH01000010.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUDH01000010.1All displayed genes belong to this local TCS context.
Neighborhood span134 751-136 965 nt2 215 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
134 751 nt136 965 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW085_RS12390GCF_003477445#DW085_RS12390
RROmpR

134 751-135 440 nt · Reverse (-)

Old locus DW085_12385RefSeq WP_022359471.1
DW085_RS12395GCF_003477445#DW085_RS12395
HKClassicCurrent focus

135 490-136 965 nt · Reverse (-)

Old locus DW085_12390RefSeq WP_118492943.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1528565Run 6 · HK · 25 sequences
Representative sequenceGCF_003477445#DW085_RS12395The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1528565

Simplified PFAM architecture for HKOC_1528565

PFAM domain coverage: 229 / 491 aa (46.6%)

1 aa491 aa
HAMP: 199-251 aaHAMPHisKA: 264-328 aaHisKAHATPase_c: 377-487 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[199-251] | HisKA[264-328] | HATPase_c[377-487]
  • Domain count: 3
  • Matched identifier: HKOC_1528565
  • Positioned domains: HAMP 199-251 ; HisKA 264-328 ; HATPase_c 377-487
Cluster members and taxonomy
Visualization

Representative gene: GCF_003477445#DW085_RS12395

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 021 · GCF_003477445
AssemblyASM347744v1 · Scaffoldhaploid
Genome composition3 864 962 bp · 48,0% GCClostridium sp. AF50-3
Signal transduction countsGenes 53 · HK 28 · RR 22CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key