Gene detail

DWZ98_RS04150

Histidine kinase, Classic

Dorea formicigenerans · GCF_003475215

ClassHKTypeClassicLength592 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003475215#DWZ98_RS04150Stable P2CS identifier used across views.
GenomeGCF_003475215Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_1100594Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_118427012.1 · A0A415N4Q5 · MIST4 DWZ98_RS04150RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length592 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 592 aa (43.6%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa592 aa
HAMP: 294-363 aa (70 aa)1His_kinase: 378-452 aa (75 aa)2HATPase_c: 473-585 aa (113 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
294-363 aa · 70 aa · 11.8% of protein
Raw tokenHAMP:294:0.000000000000487:363:70:69
2 His_kinase#2
378-452 aa · 75 aa · 12.7% of protein
Raw tokenHis_kinase:378:7.36e-33:452:75:80
3 HATPase_c#3
473-585 aa · 113 aa · 19.1% of protein
Raw tokenHATPase_c:473:0.00000000141:585:114:109
  • Raw architecture: HAMP:294:0.000000000000487:363:70:69#His_kinase:378:7.36e-33:452:75:80#HATPase_c:473:0.00000000141:585:114:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003475215::NZ_QRPD01000002.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span332496-335869Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWZ98_04150RefSeq proteinWP_118427012.1
Context group IDGCF_003475215::NZ_QRPD01000002.1::G00026
Context members
DWZ98_RS04145DWZ98_RS04150
Partner locus tags
DWZ98_RS04145DWZ98_RS04150
Partner old locus tags
DWZ98_04145DWZ98_04150
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_118427012.1Primary protein accession used for annex mappings.
UniProt accessionA0A415N4Q5Primary UniProt accession resolved in the annex database.
UniProt IDA0A415N4Q5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWZ98_RS04150Primary locus identifier stored in the genes table.
Old locus tagDWZ98_04150Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QRPD01000002.1Sequence record reported by the local genomic context database.
Genomic interval334 091-335 869 nt1 779 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span332 496-335 869 ntGCF_003475215::NZ_QRPD01000002.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003475215::NZ_QRPD01000002.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QRPD01000002.1All displayed genes belong to this local TCS context.
Neighborhood span332 496-335 869 nt3 374 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
332 496 nt335 869 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWZ98_RS04145GCF_003475215#DWZ98_RS04145
RRunclassified

332 496-334 094 nt · Forward (+)

Old locus DWZ98_04145RefSeq WP_118427010.1
DWZ98_RS04150GCF_003475215#DWZ98_RS04150
HKClassicCurrent focus

334 091-335 869 nt · Forward (+)

Old locus DWZ98_04150RefSeq WP_118427012.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1100594Run 6 · HK · 3 sequences
Representative sequenceGCF_003475215#DWZ98_RS04150The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1100594

Simplified PFAM architecture for HKOC_1100594

PFAM domain coverage: 243 / 592 aa (41.0%)

1 aa592 aa
HAMP: 311-363 aaHAMPHis_kinase: 379-453 aaHis_kinaseHATPase_c: 472-586 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[311-363] | His_kinase[379-453] | HATPase_c[472-586]
  • Domain count: 3
  • Matched identifier: HKOC_1100594
  • Positioned domains: HAMP 311-363 ; His_kinase 379-453 ; HATPase_c 472-586
Cluster members and taxonomy
Visualization

Representative gene: GCF_003475215#DWZ98_RS04150

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 486 · GCF_003475215
AssemblyASM347521v1 · Scaffoldhaploid
Genome composition3 408 767 bp · 41,0% GCDorea formicigenerans
Signal transduction countsGenes 98 · HK 48 · RR 48CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key