Gene detail

DW153_RS09525

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_003473045

ClassHKTypeClassicLength604 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003473045#DW153_RS09525Stable P2CS identifier used across views.
GenomeGCF_003473045Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1033066Run 6 · 61 sequences · id 100% · cov 80%
External referencesWP_055169462.1 · A0A396G314 · MIST4 DW153_RS09525RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length604 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage256 / 604 aa (42.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa604 aa
HAMP: 288-351 aa (64 aa)1His_kinase: 372-448 aa (77 aa)2HATPase_c: 462-576 aa (115 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-351 aa · 64 aa · 10.6% of protein
Raw tokenHAMP:288:0.000000473:351:64:69
2 His_kinase#2
372-448 aa · 77 aa · 12.7% of protein
Raw tokenHis_kinase:372:4.48e-26:448:77:80
3 HATPase_c#3
462-576 aa · 115 aa · 19.0% of protein
Raw tokenHATPase_c:462:2.05e-17:576:115:109
  • Raw architecture: HAMP:288:0.000000473:351:64:69#His_kinase:372:4.48e-26:448:77:80#HATPase_c:462:2.05e-17:576:115:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003473045::NZ_QRLD01000010.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span22219-25018Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW153_09525RefSeq proteinWP_055169462.1
Context group IDGCF_003473045::NZ_QRLD01000010.1::G00006
Context members
DW153_RS09525DW153_RS09530
Partner locus tags
DW153_RS09525DW153_RS09530
Partner old locus tags
DW153_09525DW153_09530
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055169462.1Primary protein accession used for annex mappings.
UniProt accessionA0A396G314Primary UniProt accession resolved in the annex database.
UniProt IDA0A396G314_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW153_RS09525Primary locus identifier stored in the genes table.
Old locus tagDW153_09525Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QRLD01000010.1Sequence record reported by the local genomic context database.
Genomic interval22 219-24 033 nt1 815 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span22 219-25 018 ntGCF_003473045::NZ_QRLD01000010.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003473045::NZ_QRLD01000010.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QRLD01000010.1All displayed genes belong to this local TCS context.
Neighborhood span22 219-25 018 nt2 800 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
22 219 nt25 018 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW153_RS09525GCF_003473045#DW153_RS09525
HKClassicCurrent focus

22 219-24 033 nt · Forward (+)

Old locus DW153_09525RefSeq WP_055169462.1
DW153_RS09530GCF_003473045#DW153_RS09530
RRunclassified

24 014-25 018 nt · Forward (+)

Old locus DW153_09530RefSeq WP_055169459.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1033066Run 6 · HK · 61 sequences
Representative sequenceGCF_001406655#ARA00_RS12080Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1033066

Simplified PFAM architecture for HKOC_1033066

PFAM domain coverage: 191 / 604 aa (31.6%)

1 aa604 aa
His_kinase: 373-448 aaHis_kinaseHATPase_c: 462-576 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[373-448] | HATPase_c[462-576]
  • Domain count: 2
  • Matched identifier: HKOC_1033066
  • Positioned domains: His_kinase 373-448 ; HATPase_c 462-576
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406655#ARA00_RS12080

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_003473045
AssemblyASM347304v1 · Scaffoldhaploid
Genome composition3 323 923 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key