1 HAMP#1
288-351 aa · 64 aa · 10.6% of protein
Raw token
HAMP:288:0.000000473:351:64:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DW812_RS04685
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_003468635
ClassHKTypeClassicLength604 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003468635#DW812_RS04685Stable P2CS identifier used across views.
GenomeGCF_003468635Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length604 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage256 / 604 aa (42.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa604 aa
Domain-by-domain annotation3 items
2 His_kinase#2
372-448 aa · 77 aa · 12.7% of protein
Raw token
His_kinase:372:4.48e-26:448:77:803 HATPase_c#3
462-576 aa · 115 aa · 19.0% of protein
Raw token
HATPase_c:462:2.05e-17:576:115:109- Raw architecture: HAMP:288:0.000000473:351:64:69#His_kinase:372:4.48e-26:448:77:80#HATPase_c:462:2.05e-17:576:115:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003468635::NZ_QSIR01000004.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span110930-113729Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW812_04685RefSeq proteinWP_055169462.1
Context group ID
GCF_003468635::NZ_QSIR01000004.1::G00036Context members
DW812_RS04680DW812_RS04685
Partner locus tags
DW812_RS04680DW812_RS04685
Partner old locus tags
DW812_04680DW812_04685
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_055169462.1Primary protein accession used for annex mappings.
UniProt accessionA0A396G314Primary UniProt accession resolved in the annex database.
UniProt IDA0A396G314_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDW812_RS04685Primary locus identifier stored in the genes table.
Old locus tagDW812_04685Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSIR01000004.1Sequence record reported by the local genomic context database.
Genomic interval111 915-113 729 nt1 815 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span110 930-113 729 ntGCF_003468635::NZ_QSIR01000004.1::G00036
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003468635::NZ_QSIR01000004.1::G00036Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSIR01000004.1All displayed genes belong to this local TCS context.
Neighborhood span110 930-113 729 nt2 800 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
110 930 nt113 729 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DW812_RS04680GCF_003468635#DW812_RS04680
RRunclassified
110 930-111 934 nt · Reverse (-)
DW812_RS04685GCF_003468635#DW812_RS04685
HKClassicCurrent focus
111 915-113 729 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001406655#ARA00_RS12080Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1033066
Simplified PFAM architecture for HKOC_1033066
PFAM domain coverage: 191 / 604 aa (31.6%)
1 aa604 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[373-448] | HATPase_c[462-576]
- Domain count: 2
- Matched identifier: HKOC_1033066
- Positioned domains: His_kinase 373-448 ; HATPase_c 462-576
Cluster members and taxonomy
Representative gene: GCF_001406655#ARA00_RS12080
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_003468635
AssemblyASM346863v1 · Scaffoldhaploid
Genome composition3 851 554 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 97 · HK 46 · RR 50CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key