Gene detail

DW856_RS08000

Histidine kinase, Hybrid

Roseburia intestinalis · GCF_003467725

ClassHKTypeHybridLength891 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_003467725#DW856_RS08000Stable P2CS identifier used across views.
GenomeGCF_003467725Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_0427244Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_118597653.1 · A0A3R6AX51 · MIST4 DW856_RS08000RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length891 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage289 / 891 aa (32.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa891 aa
HisKA: 206-271 aa (66 aa)1HATPase_c: 318-434 aa (117 aa)2Response_reg: 467-572 aa (106 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
206-271 aa · 66 aa · 7.4% of protein
Raw tokenHisKA:206:9.21e-19:271:66:64
2 HATPase_c#2
318-434 aa · 117 aa · 13.1% of protein
Raw tokenHATPase_c:318:2.81e-29:434:117:109
3 Response_reg#3
467-572 aa · 106 aa · 11.9% of protein
Raw tokenResponse_reg:467:7.78e-21:572:106:111
  • Raw architecture: HisKA:206:9.21e-19:271:66:64#HATPase_c:318:2.81e-29:434:117:109#Response_reg:467:7.78e-21:572:106:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_003467725::NZ_QSHO01000006.1::G00050
Group size33 locus tags listed below.
HK / RR2 / 1Counts resolved for the local TCS neighborhood.
Context span55647-62075Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW856_07995RefSeq proteinWP_118597653.1
Context group IDGCF_003467725::NZ_QSHO01000006.1::G00050
Context members
DW856_RS07990DW856_RS07995DW856_RS08000
Partner locus tags
DW856_RS07990DW856_RS07995DW856_RS08000
Partner old locus tags
DW856_07985DW856_07990DW856_07995

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_118597653.1Primary protein accession used for annex mappings.
UniProt accessionA0A3R6AX51Primary UniProt accession resolved in the annex database.
UniProt IDA0A3R6AX51_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW856_RS08000Primary locus identifier stored in the genes table.
Old locus tagDW856_07995Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSHO01000006.1Sequence record reported by the local genomic context database.
Genomic interval59 400-62 075 nt2 676 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span55 647-62 075 ntGCF_003467725::NZ_QSHO01000006.1::G00050

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003467725::NZ_QSHO01000006.1::G00050

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSHO01000006.1All displayed genes belong to this local TCS context.
Neighborhood span55 647-62 075 nt6 429 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
55 647 nt62 075 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

DW856_RS07990GCF_003467725#DW856_RS07990
RRRpfG

55 647-56 699 nt · Forward (+)

Old locus DW856_07985RefSeq WP_006857201.1
DW856_RS07995GCF_003467725#DW856_RS07995
HKUnorthodox

56 711-59 407 nt · Forward (+)

Old locus DW856_07990RefSeq WP_243091474.1
DW856_RS08000GCF_003467725#DW856_RS08000
HKHybridCurrent focus

59 400-62 075 nt · Forward (+)

Old locus DW856_07995RefSeq WP_118597653.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0427244Run 6 · HK · 1 sequences
Representative sequenceGCF_003467725#DW856_RS08000The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + DegV4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0427244

Simplified PFAM architecture for HKOC_0427244

PFAM domain coverage: 561 / 891 aa (63.0%)

1 aa891 aa
HisKA: 206-271 aaHisKAHATPase_c: 318-433 aaHATPase_cResponse_reg: 467-572 aaResponse_regDegV: 617-889 aaDegV
HisKAHATPase_cResponse_regDegV
  • Simplified architecture: HisKA + HATPase_c + Response_reg + DegV
  • Raw architecture: HisKA[206-271] | HATPase_c[318-433] | Response_reg[467-572] | DegV[617-889]
  • Domain count: 4
  • Matched identifier: HKOC_0427244
  • Positioned domains: HisKA 206-271 ; HATPase_c 318-433 ; Response_reg 467-572 ; DegV 617-889
Cluster members and taxonomy
Visualization

Representative gene: GCF_003467725#DW856_RS08000

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 166 486 · GCF_003467725
AssemblyASM346772v1 · Scaffoldhaploid
Genome composition4 253 056 bp · 42,0% GCRoseburia intestinalis
Signal transduction countsGenes 106 · HK 47 · RR 56CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key