Gene detail

DW856_RS03135

Histidine kinase, Classic

Roseburia intestinalis · GCF_003467725

ClassHKTypeClassicLength613 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003467725#DW856_RS03135Stable P2CS identifier used across views.
GenomeGCF_003467725Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_0994736Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_118591989.1 · A0A413SFG5 · MIST4 DW856_RS03135RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1His_kinaseHATPase_c
Protein length613 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage425 / 613 aa (69.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa613 aa
dCache_1: 55-293 aa (239 aa)1His_kinase: 394-473 aa (80 aa)2HATPase_c: 489-594 aa (106 aa)3
Domain-by-domain annotation3 items
1 dCache_1#1
55-293 aa · 239 aa · 39.0% of protein
Raw tokendCache_1:55:6.72e-17:293:243:195
2 His_kinase#2
394-473 aa · 80 aa · 13.1% of protein
Raw tokenHis_kinase:394:4.23e-34:473:80:80
3 HATPase_c#3
489-594 aa · 106 aa · 17.3% of protein
Raw tokenHATPase_c:489:9.3e-19:594:109:109
  • Raw architecture: dCache_1:55:6.72e-17:293:243:195#His_kinase:394:4.23e-34:473:80:80#HATPase_c:489:9.3e-19:594:109:109
  • Domain description: 1 dCache_1,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003467725::NZ_QSHO01000002.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span269740-273179Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW856_03130RefSeq proteinWP_118591989.1
Context group IDGCF_003467725::NZ_QSHO01000002.1::G00030
Context members
DW856_RS03135DW856_RS03140
Partner locus tags
DW856_RS03135DW856_RS03140
Partner old locus tags
DW856_03130DW856_03135
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_118591989.1Primary protein accession used for annex mappings.
UniProt accessionA0A413SFG5Primary UniProt accession resolved in the annex database.
UniProt IDA0A413SFG5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW856_RS03135Primary locus identifier stored in the genes table.
Old locus tagDW856_03130Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSHO01000002.1Sequence record reported by the local genomic context database.
Genomic interval269 740-271 581 nt1 842 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span269 740-273 179 ntGCF_003467725::NZ_QSHO01000002.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003467725::NZ_QSHO01000002.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSHO01000002.1All displayed genes belong to this local TCS context.
Neighborhood span269 740-273 179 nt3 440 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
269 740 nt273 179 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW856_RS03135GCF_003467725#DW856_RS03135
HKClassicCurrent focus

269 740-271 581 nt · Reverse (-)

Old locus DW856_03130RefSeq WP_118591989.1
DW856_RS03140GCF_003467725#DW856_RS03140
RRunclassified

271 578-273 179 nt · Reverse (-)

Old locus DW856_03135RefSeq WP_015520937.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0994736Run 6 · HK · 3 sequences
Representative sequenceGCF_003467035#DW927_RS12880Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0994736

Simplified PFAM architecture for HKOC_0994736

PFAM domain coverage: 414 / 613 aa (67.5%)

1 aa613 aa
dCache_1: 63-293 aadCache_1His_kinase: 394-471 aaHis_kinaseHATPase_c: 490-594 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[63-293] | His_kinase[394-471] | HATPase_c[490-594]
  • Domain count: 3
  • Matched identifier: HKOC_0994736
  • Positioned domains: dCache_1 63-293 ; His_kinase 394-471 ; HATPase_c 490-594
Cluster members and taxonomy
Visualization

Representative gene: GCF_003467035#DW927_RS12880

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 166 486 · GCF_003467725
AssemblyASM346772v1 · Scaffoldhaploid
Genome composition4 253 056 bp · 42,0% GCRoseburia intestinalis
Signal transduction countsGenes 106 · HK 47 · RR 56CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key