1 HAMP#1
300-369 aa · 70 aa · 11.8% of protein
Raw token
HAMP:300:0.00000000201:369:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DW856_RS02390
Histidine kinase, Classic
Roseburia intestinalis · GCF_003467725
ClassHKTypeClassicLength592 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003467725#DW856_RS02390Stable P2CS identifier used across views.
GenomeGCF_003467725Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length592 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage252 / 592 aa (42.6%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa592 aa
Domain-by-domain annotation3 items
2 His_kinase#2
384-463 aa · 80 aa · 13.5% of protein
Raw token
His_kinase:384:1.18e-28:463:80:803 HATPase_c#3
482-583 aa · 102 aa · 17.2% of protein
Raw token
HATPase_c:482:0.000000000000145:583:106:109- Raw architecture: HAMP:300:0.00000000201:369:70:69#His_kinase:384:1.18e-28:463:80:80#HATPase_c:482:0.000000000000145:583:106:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003467725::NZ_QSHO01000002.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span94789-98086Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW856_02390RefSeq proteinWP_022113093.1
Context group ID
GCF_003467725::NZ_QSHO01000002.1::G00027Context members
DW856_RS02390DW856_RS02395
Partner locus tags
DW856_RS02390DW856_RS02395
Partner old locus tags
DW856_02390DW856_02395
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_022113093.1Primary protein accession used for annex mappings.
UniProt accessionA0A173UC31Primary UniProt accession resolved in the annex database.
UniProt IDA0A173UC31_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDW856_RS02390Primary locus identifier stored in the genes table.
Old locus tagDW856_02390Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSHO01000002.1Sequence record reported by the local genomic context database.
Genomic interval94 789-96 567 nt1 779 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span94 789-98 086 ntGCF_003467725::NZ_QSHO01000002.1::G00027
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003467725::NZ_QSHO01000002.1::G00027Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSHO01000002.1All displayed genes belong to this local TCS context.
Neighborhood span94 789-98 086 nt3 298 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
94 789 nt98 086 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DW856_RS02390GCF_003467725#DW856_RS02390
HKClassicCurrent focus
94 789-96 567 nt · Reverse (-)
DW856_RS02395GCF_003467725#DW856_RS02395
RRunclassified
96 560-98 086 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001406435#ARA28_RS09560Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1099561
Simplified PFAM architecture for HKOC_1099561
PFAM domain coverage: 233 / 592 aa (39.4%)
1 aa592 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[318-368] | His_kinase[384-462] | HATPase_c[481-583]
- Domain count: 3
- Matched identifier: HKOC_1099561
- Positioned domains: HAMP 318-368 ; His_kinase 384-462 ; HATPase_c 481-583
Cluster members and taxonomy
Representative gene: GCF_001406435#ARA28_RS09560
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 166 486 · GCF_003467725
AssemblyASM346772v1 · Scaffoldhaploid
Genome composition4 253 056 bp · 42,0% GCRoseburia intestinalis
Signal transduction countsGenes 106 · HK 47 · RR 56CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key