Gene detail

DW746_RS08080

Histidine kinase, Classic

Blautia sp. AM28-36 · GCF_003462165

ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003462165#DW746_RS08080Stable P2CS identifier used across views.
GenomeGCF_003462165Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1184244Run 6 · 11 sequences · id 100% · cov 80% · representative
External referencesWP_158568552.1 · MIST4 DW746_RS08080RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 576 aa (43.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
HAMP: 288-357 aa (70 aa)1His_kinase: 373-445 aa (73 aa)2HATPase_c: 463-568 aa (106 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-357 aa · 70 aa · 12.2% of protein
Raw tokenHAMP:288:0.000000000000195:357:70:69
2 His_kinase#2
373-445 aa · 73 aa · 12.7% of protein
Raw tokenHis_kinase:373:4.02e-29:445:73:80
3 HATPase_c#3
463-568 aa · 106 aa · 18.4% of protein
Raw tokenHATPase_c:463:0.00000000000000782:568:115:109
  • Raw architecture: HAMP:288:0.000000000000195:357:70:69#His_kinase:373:4.02e-29:445:73:80#HATPase_c:463:0.00000000000000782:568:115:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003462165::NZ_QTYM01000004.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span103485-106740Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW746_08090RefSeq proteinWP_158568552.1
Context group IDGCF_003462165::NZ_QTYM01000004.1::G00046
Context members
DW746_RS08080DW746_RS18630
Partner locus tags
DW746_RS08080DW746_RS18630
Partner old locus tags
DW746_08090DW746_08095
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_158568552.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW746_RS08080Primary locus identifier stored in the genes table.
Old locus tagDW746_08090Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTYM01000004.1Sequence record reported by the local genomic context database.
Genomic interval103 485-105 215 nt1 731 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span103 485-106 740 ntGCF_003462165::NZ_QTYM01000004.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003462165::NZ_QTYM01000004.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTYM01000004.1All displayed genes belong to this local TCS context.
Neighborhood span103 485-106 740 nt3 256 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
103 485 nt106 740 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW746_RS08080GCF_003462165#DW746_RS08080
HKClassicCurrent focus

103 485-105 215 nt · Reverse (-)

Old locus DW746_08090RefSeq WP_158568552.1
DW746_RS18630GCF_003462165#DW746_RS18630
RRunclassified

105 217-106 740 nt · Reverse (-)

Old locus DW746_08095RefSeq WP_117761307.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1184244Run 6 · HK · 11 sequences
Representative sequenceGCF_003462165#DW746_RS08080The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1184244

Simplified PFAM architecture for HKOC_1184244

PFAM domain coverage: 230 / 576 aa (39.9%)

1 aa576 aa
HAMP: 307-357 aaHAMPHis_kinase: 373-445 aaHis_kinaseHATPase_c: 463-568 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[307-357] | His_kinase[373-445] | HATPase_c[463-568]
  • Domain count: 3
  • Matched identifier: HKOC_1184244
  • Positioned domains: HAMP 307-357 ; His_kinase 373-445 ; HATPase_c 463-568
Cluster members and taxonomy
Visualization

Representative gene: GCF_003462165#DW746_RS08080

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 974 · GCF_003462165
AssemblyASM346216v1 · Scaffoldhaploid
Genome composition3 801 735 bp · 47,0% GCBlautia sp. AM28-36
Signal transduction countsGenes 102 · HK 51 · RR 49CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key