Gene detail

DW746_RS06330

Histidine kinase, Classic

Blautia sp. AM28-36 · GCF_003462165

ClassHKTypeClassicLength492 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003462165#DW746_RS06330Stable P2CS identifier used across views.
GenomeGCF_003462165Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1522308Run 6 · 38 sequences · id 100% · cov 80%
External referencesWP_022462210.1 · A0AAE3F2L1 · MIST4 DW746_RS06330RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length492 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 492 aa (49.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa492 aa
HAMP: 194-262 aa (69 aa)1HisKA: 266-331 aa (66 aa)2HATPase_c: 379-488 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
194-262 aa · 69 aa · 14.0% of protein
Raw tokenHAMP:194:0.000000000219:262:69:69
2 HisKA#2
266-331 aa · 66 aa · 13.4% of protein
Raw tokenHisKA:266:0.00000000000726:331:66:64
3 HATPase_c#3
379-488 aa · 110 aa · 22.4% of protein
Raw tokenHATPase_c:379:5.43e-29:488:110:109
  • Raw architecture: HAMP:194:0.000000000219:262:69:69#HisKA:266:0.00000000000726:331:66:64#HATPase_c:379:5.43e-29:488:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003462165::NZ_QTYM01000003.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span105922-108034Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW746_06340RefSeq proteinWP_022462210.1
Context group IDGCF_003462165::NZ_QTYM01000003.1::G00041
Context members
DW746_RS06325DW746_RS06330
Partner locus tags
DW746_RS06325DW746_RS06330
Partner old locus tags
DW746_06335DW746_06340
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022462210.1Primary protein accession used for annex mappings.
UniProt accessionA0AAE3F2L1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAE3F2L1_9FIRMDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW746_RS06330Primary locus identifier stored in the genes table.
Old locus tagDW746_06340Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTYM01000003.1Sequence record reported by the local genomic context database.
Genomic interval106 556-108 034 nt1 479 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span105 922-108 034 ntGCF_003462165::NZ_QTYM01000003.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003462165::NZ_QTYM01000003.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTYM01000003.1All displayed genes belong to this local TCS context.
Neighborhood span105 922-108 034 nt2 113 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
105 922 nt108 034 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW746_RS06325GCF_003462165#DW746_RS06325
RROmpR

105 922-106 611 nt · Forward (+)

Old locus DW746_06335RefSeq WP_022462209.1
DW746_RS06330GCF_003462165#DW746_RS06330
HKClassicCurrent focus

106 556-108 034 nt · Forward (+)

Old locus DW746_06340RefSeq WP_022462210.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1522308Run 6 · HK · 38 sequences
Representative sequenceGCF_003460955#DWY63_RS04805Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1522308

Simplified PFAM architecture for HKOC_1522308

PFAM domain coverage: 176 / 492 aa (35.8%)

1 aa492 aa
HisKA: 266-331 aaHisKAHATPase_c: 379-488 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[266-331] | HATPase_c[379-488]
  • Domain count: 2
  • Matched identifier: HKOC_1522308
  • Positioned domains: HisKA 266-331 ; HATPase_c 379-488
Cluster members and taxonomy
Visualization

Representative gene: GCF_003460955#DWY63_RS04805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 974 · GCF_003462165
AssemblyASM346216v1 · Scaffoldhaploid
Genome composition3 801 735 bp · 47,0% GCBlautia sp. AM28-36
Signal transduction countsGenes 102 · HK 51 · RR 49CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key