Gene detail

DWV73_RS00390

Histidine kinase, Classic

Clostridium sp. AF12-41 · GCF_003461685

ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003461685#DWV73_RS00390Stable P2CS identifier used across views.
GenomeGCF_003461685Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1058356Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_117795062.1 · MIST4 DWV73_RS00390RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage496 / 599 aa (82.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
dCache_1: 47-284 aa (238 aa)1HAMP: 301-369 aa (69 aa)2His_kinase: 386-464 aa (79 aa)3HATPase_c: 480-589 aa (110 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
47-284 aa · 238 aa · 39.7% of protein
Raw tokendCache_1:47:0.000000000000161:284:244:195
2 HAMP#2
301-369 aa · 69 aa · 11.5% of protein
Raw tokenHAMP:301:0.0000000000235:369:69:69
3 His_kinase#3
386-464 aa · 79 aa · 13.2% of protein
Raw tokenHis_kinase:386:4.78e-35:464:79:80
4 HATPase_c#4
480-589 aa · 110 aa · 18.4% of protein
Raw tokenHATPase_c:480:1.58e-18:589:112:109
  • Raw architecture: dCache_1:47:0.000000000000161:284:244:195#HAMP:301:0.0000000000235:369:69:69#His_kinase:386:4.78e-35:464:79:80#HATPase_c:480:1.58e-18:589:112:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003461685::NZ_QTXO01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span92712-96139Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWV73_00390RefSeq proteinWP_117795062.1
Context group IDGCF_003461685::NZ_QTXO01000001.1::G00002
Context members
DWV73_RS00385DWV73_RS00390
Partner locus tags
DWV73_RS00385DWV73_RS00390
Partner old locus tags
DWV73_00385DWV73_00390
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117795062.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWV73_RS00390Primary locus identifier stored in the genes table.
Old locus tagDWV73_00390Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTXO01000001.1Sequence record reported by the local genomic context database.
Genomic interval94 340-96 139 nt1 800 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span92 712-96 139 ntGCF_003461685::NZ_QTXO01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003461685::NZ_QTXO01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTXO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span92 712-96 139 nt3 428 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
92 712 nt96 139 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWV73_RS00385GCF_003461685#DWV73_RS00385
RRunclassified

92 712-94 340 nt · Forward (+)

Old locus DWV73_00385RefSeq WP_107001617.1
DWV73_RS00390GCF_003461685#DWV73_RS00390
HKClassicCurrent focus

94 340-96 139 nt · Forward (+)

Old locus DWV73_00390RefSeq WP_117795062.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1058356Run 6 · HK · 5 sequences
Representative sequenceGCF_003461685#DWV73_RS00390The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1058356

Simplified PFAM architecture for HKOC_1058356

PFAM domain coverage: 474 / 599 aa (79.1%)

1 aa599 aa
dCache_1: 49-283 aadCache_1HAMP: 319-369 aaHAMPHis_kinase: 386-464 aaHis_kinaseHATPase_c: 479-587 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[49-283] | HAMP[319-369] | His_kinase[386-464] | HATPase_c[479-587]
  • Domain count: 4
  • Matched identifier: HKOC_1058356
  • Positioned domains: dCache_1 49-283 ; HAMP 319-369 ; His_kinase 386-464 ; HATPase_c 479-587
Cluster members and taxonomy
Visualization

Representative gene: GCF_003461685#DWV73_RS00390

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 994 · GCF_003461685
AssemblyASM346168v1 · Scaffoldhaploid
Genome composition2 783 658 bp · 49,0% GCClostridium sp. AF12-41
Signal transduction countsGenes 51 · HK 27 · RR 22CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key