Gene detail

DWZ44_RS06490

Histidine kinase, Hybrid

Blautia sp. AF32-4BH · GCF_003460565

ClassHKTypeHybridLength1058 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003460565#DWZ44_RS06490Stable P2CS identifier used across views.
GenomeGCF_003460565Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_0253738Run 6 · 7 sequences · id 100% · cov 80% · representative
External referencesWP_117761881.1 · MIST4 DWZ44_RS06490RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PilJGGDEFHisKAHATPase_cResponse_reg
Protein length1058 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage541 / 1058 aa (51.1%)Merged over positioned domains only.
Domain description1 PilJ,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1058 aa
PilJ: 38-124 aa (87 aa)1GGDEF: 199-350 aa (152 aa)2HisKA: 678-744 aa (67 aa)3HATPase_c: 791-909 aa (119 aa)4Response_reg: 933-1048 aa (116 aa)5
Domain-by-domain annotation5 items
1 PilJ#1
38-124 aa · 87 aa · 8.2% of protein
Raw tokenPilJ:38:0.0000319:124:100:112
2 GGDEF#2
199-350 aa · 152 aa · 14.4% of protein
Raw tokenGGDEF:199:3.57e-21:350:158:160
3 HisKA#3
678-744 aa · 67 aa · 6.3% of protein
Raw tokenHisKA:678:0.0000000000000451:744:67:64
4 HATPase_c#4
791-909 aa · 119 aa · 11.2% of protein
Raw tokenHATPase_c:791:1.97e-27:909:119:109
5 Response_reg#5
933-1048 aa · 116 aa · 11.0% of protein
Raw tokenResponse_reg:933:4.84e-28:1048:116:111
  • Raw architecture: PilJ:38:0.0000319:124:100:112#GGDEF:199:3.57e-21:350:158:160#HisKA:678:0.0000000000000451:744:67:64#HATPase_c:791:1.97e-27:909:119:109#Response_reg:933:4.84e-28:1048:116:111
  • Domain description: 1 PilJ,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003460565::NZ_QTVL01000004.1::G00035
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span58524-61700Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWZ44_06505RefSeq proteinWP_117761881.1
Context group IDGCF_003460565::NZ_QTVL01000004.1::G00035
Context members
DWZ44_RS06490
Partner locus tags
DWZ44_RS06490
Partner old locus tags
DWZ44_06505
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117761881.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWZ44_RS06490Primary locus identifier stored in the genes table.
Old locus tagDWZ44_06505Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTVL01000004.1Sequence record reported by the local genomic context database.
Genomic interval58 524-61 700 nt3 177 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span58 524-61 700 ntGCF_003460565::NZ_QTVL01000004.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003460565::NZ_QTVL01000004.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTVL01000004.1All displayed genes belong to this local TCS context.
Neighborhood span58 524-61 700 nt3 177 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
58 524 nt61 700 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

DWZ44_RS06490GCF_003460565#DWZ44_RS06490
HKHybridCurrent focus

58 524-61 700 nt · Reverse (-)

Old locus DWZ44_06505RefSeq WP_117761881.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0253738Run 6 · HK · 7 sequences
Representative sequenceGCF_003460565#DWZ44_RS06490The current gene is the representative for this cluster.
PFAM architectureGGDEF + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0253738

Simplified PFAM architecture for HKOC_0253738

PFAM domain coverage: 452 / 1058 aa (42.7%)

1 aa1058 aa
GGDEF: 200-352 aaGGDEFHisKA: 678-744 aaHisKAHATPase_c: 792-907 aaHATPase_cResponse_reg: 933-1048 aaResponse_reg
GGDEFHisKAHATPase_cResponse_reg
  • Simplified architecture: GGDEF + HisKA + HATPase_c + Response_reg
  • Raw architecture: GGDEF[200-352] | HisKA[678-744] | HATPase_c[792-907] | Response_reg[933-1048]
  • Domain count: 4
  • Matched identifier: HKOC_0253738
  • Positioned domains: GGDEF 200-352 ; HisKA 678-744 ; HATPase_c 792-907 ; Response_reg 933-1048
Cluster members and taxonomy
Visualization

Representative gene: GCF_003460565#DWZ44_RS06490

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 967 · GCF_003460565
AssemblyASM346056v1 · Scaffoldhaploid
Genome composition3 839 213 bp · 46,5% GCBlautia sp. AF32-4BH
Signal transduction countsGenes 91 · HK 46 · RR 43CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key