Gene detail

DWY88_RS00635

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_003457855

ClassHKTypeClassicLength463 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003457855#DWY88_RS00635Stable P2CS identifier used across views.
GenomeGCF_003457855Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1795459Run 6 · 97 sequences · id 100% · cov 80%
External referencesWP_004843307.1 · A7B489 · MIST4 DWY88_RS00635RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length463 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 463 aa (52.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa463 aa
HAMP: 166-233 aa (68 aa)1HisKA: 237-302 aa (66 aa)2HATPase_c: 350-460 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-233 aa · 68 aa · 14.7% of protein
Raw tokenHAMP:166:0.0000000000511:233:68:69
2 HisKA#2
237-302 aa · 66 aa · 14.3% of protein
Raw tokenHisKA:237:0.00000000000012:302:66:64
3 HATPase_c#3
350-460 aa · 111 aa · 24.0% of protein
Raw tokenHATPase_c:350:1.06e-32:460:111:109
  • Raw architecture: HAMP:166:0.0000000000511:233:68:69#HisKA:237:0.00000000000012:302:66:64#HATPase_c:350:1.06e-32:460:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003457855::NZ_QRTJ01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span124070-126191Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWY88_00630RefSeq proteinWP_004843307.1
Context group IDGCF_003457855::NZ_QRTJ01000001.1::G00002
Context members
DWY88_RS00635DWY88_RS00640
Partner locus tags
DWY88_RS00635DWY88_RS00640
Partner old locus tags
DWY88_00630DWY88_00635
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004843307.1Primary protein accession used for annex mappings.
UniProt accessionA7B489Primary UniProt accession resolved in the annex database.
UniProt IDA7B489_MEDG7Display identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWY88_RS00635Primary locus identifier stored in the genes table.
Old locus tagDWY88_00630Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QRTJ01000001.1Sequence record reported by the local genomic context database.
Genomic interval124 070-125 461 nt1 392 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span124 070-126 191 ntGCF_003457855::NZ_QRTJ01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003457855::NZ_QRTJ01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QRTJ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span124 070-126 191 nt2 122 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
124 070 nt126 191 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWY88_RS00635GCF_003457855#DWY88_RS00635
HKClassicCurrent focus

124 070-125 461 nt · Reverse (-)

Old locus DWY88_00630RefSeq WP_004843307.1
DWY88_RS00640GCF_003457855#DWY88_RS00640
RROmpR

125 499-126 191 nt · Reverse (-)

Old locus DWY88_00635RefSeq WP_009243920.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1795459Run 6 · HK · 97 sequences
Representative sequenceGCF_000169475#RUMGNA_RS10375Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1795459

Simplified PFAM architecture for HKOC_1795459

PFAM domain coverage: 229 / 463 aa (49.5%)

1 aa463 aa
HAMP: 181-233 aaHAMPHisKA: 238-302 aaHisKAHATPase_c: 350-460 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[181-233] | HisKA[238-302] | HATPase_c[350-460]
  • Domain count: 3
  • Matched identifier: HKOC_1795459
  • Positioned domains: HAMP 181-233 ; HisKA 238-302 ; HATPase_c 350-460
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169475#RUMGNA_RS10375

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_003457855
AssemblyASM345785v1 · Scaffoldhaploid
Genome composition3 802 386 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 98 · HK 46 · RR 51CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key