1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw token
HisKA:148:0.0000000000000537:211:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIF102859_RS18080
Histidine kinase, Classic
Clostridioides difficile · GCF_003456975
ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003456975#CDIF102859_RS18080Stable P2CS identifier used across views.
GenomeGCF_003456975Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw token
HATPase_c:260:3.58e-25:368:110:109- Raw architecture: HisKA:148:0.0000000000000537:211:64:64#HATPase_c:260:3.58e-25:368:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003456975::NZ_CP020378.1::G00050
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3806043-3807892Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF102859_03670RefSeq proteinWP_045146213.1
Context group ID
GCF_003456975::NZ_CP020378.1::G00050Context members
CDIF102859_RS18080CDIF102859_RS18085
Partner locus tags
CDIF102859_RS18080CDIF102859_RS18085
Partner old locus tags
CDIF102859_03670CDIF102859_03671
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_045146213.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIF102859_RS18080Primary locus identifier stored in the genes table.
Old locus tagCDIF102859_03670Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP020378.1Sequence record reported by the local genomic context database.
Genomic interval3 806 043-3 807 158 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 806 043-3 807 892 ntGCF_003456975::NZ_CP020378.1::G00050
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003456975::NZ_CP020378.1::G00050Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP020378.1All displayed genes belong to this local TCS context.
Neighborhood span3 806 043-3 807 892 nt1 850 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 806 043 nt3 807 892 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDIF102859_RS18080GCF_003456975#CDIF102859_RS18080
HKClassicCurrent focus
3 806 043-3 807 158 nt · Reverse (-)
CDIF102859_RS18085GCF_003456975#CDIF102859_RS18085
RROmpR
3 807 194-3 807 892 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002165155#DCQ05_RS13165Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2677086
Simplified PFAM architecture for HKOC_2677086
PFAM domain coverage: 174 / 371 aa (46.9%)
1 aa371 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[149-213] | HATPase_c[261-369]
- Domain count: 2
- Matched identifier: HKOC_2677086
- Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Representative gene: GCF_002165155#DCQ05_RS13165
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003456975
AssemblyASM345697v1 · Complete Genomehaploid
Genome composition4 247 015 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 43 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key