Gene detail

DXD36_RS09425

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_003436535

ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003436535#DXD36_RS09425Stable P2CS identifier used across views.
GenomeGCF_003436535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1047501Run 6 · 70 sequences · id 100% · cov 80%
External referencesWP_023924249.1 · A0A829NH68 · MIST4 DXD36_RS09425RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage505 / 601 aa (84.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
dCache_1: 44-287 aa (244 aa)1HAMP: 306-375 aa (70 aa)2His_kinase: 390-469 aa (80 aa)3HATPase_c: 481-591 aa (111 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
44-287 aa · 244 aa · 40.6% of protein
Raw tokendCache_1:44:1.75e-19:287:248:195
2 HAMP#2
306-375 aa · 70 aa · 11.6% of protein
Raw tokenHAMP:306:0.00000000000104:375:70:69
3 His_kinase#3
390-469 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:390:2.78e-36:469:80:80
4 HATPase_c#4
481-591 aa · 111 aa · 18.5% of protein
Raw tokenHATPase_c:481:6.74e-16:591:115:109
  • Raw architecture: dCache_1:44:1.75e-19:287:248:195#HAMP:306:0.00000000000104:375:70:69#His_kinase:390:2.78e-36:469:80:80#HATPase_c:481:6.74e-16:591:115:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003436535::NZ_QSPZ01000015.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span28097-31510Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXD36_09425RefSeq proteinWP_023924249.1
Context group IDGCF_003436535::NZ_QSPZ01000015.1::G00006
Context members
DXD36_RS09420DXD36_RS09425
Partner locus tags
DXD36_RS09420DXD36_RS09425
Partner old locus tags
DXD36_09420DXD36_09425
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_023924249.1Primary protein accession used for annex mappings.
UniProt accessionA0A829NH68Primary UniProt accession resolved in the annex database.
UniProt IDA0A829NH68_MEDG5Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXD36_RS09425Primary locus identifier stored in the genes table.
Old locus tagDXD36_09425Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSPZ01000015.1Sequence record reported by the local genomic context database.
Genomic interval29 705-31 510 nt1 806 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span28 097-31 510 ntGCF_003436535::NZ_QSPZ01000015.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003436535::NZ_QSPZ01000015.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSPZ01000015.1All displayed genes belong to this local TCS context.
Neighborhood span28 097-31 510 nt3 414 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
28 097 nt31 510 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DXD36_RS09420GCF_003436535#DXD36_RS09420
RRunclassified

28 097-29 701 nt · Forward (+)

Old locus DXD36_09420RefSeq WP_009244981.1
DXD36_RS09425GCF_003436535#DXD36_RS09425
HKClassicCurrent focus

29 705-31 510 nt · Forward (+)

Old locus DXD36_09425RefSeq WP_023924249.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1047501Run 6 · HK · 70 sequences
Representative sequenceGCF_000169475#RUMGNA_RS04660Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1047501

Simplified PFAM architecture for HKOC_1047501

PFAM domain coverage: 484 / 601 aa (80.5%)

1 aa601 aa
dCache_1: 45-287 aadCache_1HAMP: 322-374 aaHAMPHis_kinase: 390-469 aaHis_kinaseHATPase_c: 484-591 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[45-287] | HAMP[322-374] | His_kinase[390-469] | HATPase_c[484-591]
  • Domain count: 4
  • Matched identifier: HKOC_1047501
  • Positioned domains: dCache_1 45-287 ; HAMP 322-374 ; His_kinase 390-469 ; HATPase_c 484-591
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169475#RUMGNA_RS04660

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_003436535
AssemblyASM343653v1 · Scaffoldhaploid
Genome composition3 396 357 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 81 · HK 38 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key