Gene detail

DW642_RS12255

Histidine kinase, Classic

Blautia sp. AM23-13AC · GCF_003435675

ClassHKTypeClassicLength571 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003435675#DW642_RS12255Stable P2CS identifier used across views.
GenomeGCF_003435675Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1208387Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_158555024.1 · MIST4 DW642_RS12255RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length571 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage260 / 571 aa (45.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa571 aa
HAMP: 271-346 aa (76 aa)1His_kinase: 361-439 aa (79 aa)2HATPase_c: 458-562 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
271-346 aa · 76 aa · 13.3% of protein
Raw tokenHAMP:271:0.0000000000113:346:76:69
2 His_kinase#2
361-439 aa · 79 aa · 13.8% of protein
Raw tokenHis_kinase:361:3.68e-23:439:80:80
3 HATPase_c#3
458-562 aa · 105 aa · 18.4% of protein
Raw tokenHATPase_c:458:0.000000254:562:107:109
  • Raw architecture: HAMP:271:0.0000000000113:346:76:69#His_kinase:361:3.68e-23:439:80:80#HATPase_c:458:0.000000254:562:107:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003435675::NZ_QTUL01000012.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3667-6998Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW642_12230RefSeq proteinWP_158555024.1
Context group IDGCF_003435675::NZ_QTUL01000012.1::G00008
Context members
DW642_RS12255DW642_RS12260
Partner locus tags
DW642_RS12255DW642_RS12260
Partner old locus tags
DW642_12230DW642_12235
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_158555024.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW642_RS12255Primary locus identifier stored in the genes table.
Old locus tagDW642_12230Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTUL01000012.1Sequence record reported by the local genomic context database.
Genomic interval3 667-5 382 nt1 716 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 667-6 998 ntGCF_003435675::NZ_QTUL01000012.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003435675::NZ_QTUL01000012.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTUL01000012.1All displayed genes belong to this local TCS context.
Neighborhood span3 667-6 998 nt3 332 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 667 nt6 998 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW642_RS12255GCF_003435675#DW642_RS12255
HKClassicCurrent focus

3 667-5 382 nt · Forward (+)

Old locus DW642_12230RefSeq WP_158555024.1
DW642_RS12260GCF_003435675#DW642_RS12260
RRunclassified

5 418-6 998 nt · Forward (+)

Old locus DW642_12235RefSeq WP_158555025.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1208387Run 6 · HK · 1 sequences
Representative sequenceGCF_003435675#DW642_RS12255The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1208387

Simplified PFAM architecture for HKOC_1208387

PFAM domain coverage: 231 / 571 aa (40.5%)

1 aa571 aa
HAMP: 294-344 aaHAMPHis_kinase: 364-437 aaHis_kinaseHATPase_c: 458-563 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[294-344] | His_kinase[364-437] | HATPase_c[458-563]
  • Domain count: 3
  • Matched identifier: HKOC_1208387
  • Positioned domains: HAMP 294-344 ; His_kinase 364-437 ; HATPase_c 458-563
Cluster members and taxonomy
Visualization

Representative gene: GCF_003435675#DW642_RS12255

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 971 · GCF_003435675
AssemblyASM343567v1 · Scaffoldhaploid
Genome composition3 443 045 bp · 47,5% GCBlautia sp. AM23-13AC
Signal transduction countsGenes 102 · HK 54 · RR 46CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key