Gene detail

DWZ25_RS00435

Histidine kinase, Classic

Faecalibacterium prausnitzii · GCF_003433905

ClassHKTypeClassicLength449 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003433905#DWZ25_RS00435Stable P2CS identifier used across views.
GenomeGCF_003433905Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_1973303Run 6 · 36 sequences · id 100% · cov 80%
External referencesWP_005925704.1 · A8SF25 · MIST4 DWZ25_RS00435RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHisKAHATPase_c
Protein length449 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 449 aa (52.6%)Merged over positioned domains only.
Domain description1 sCache_like,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa449 aa
sCache_like: 72-130 aa (59 aa)1HisKA: 223-288 aa (66 aa)2HATPase_c: 336-446 aa (111 aa)3
Domain-by-domain annotation3 items
1 sCache_like#1
72-130 aa · 59 aa · 13.1% of protein
Raw tokensCache_like:72:0.00000598:130:59:114
2 HisKA#2
223-288 aa · 66 aa · 14.7% of protein
Raw tokenHisKA:223:1.58e-19:288:66:64
3 HATPase_c#3
336-446 aa · 111 aa · 24.7% of protein
Raw tokenHATPase_c:336:3.51e-29:446:111:109
  • Raw architecture: sCache_like:72:0.00000598:130:59:114#HisKA:223:1.58e-19:288:66:64#HATPase_c:336:3.51e-29:446:111:109
  • Domain description: 1 sCache_like,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003433905::NZ_QVES01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span74900-76932Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWZ25_00435RefSeq proteinWP_005925704.1
Context group IDGCF_003433905::NZ_QVES01000001.1::G00001
Context members
DWZ25_RS00435DWZ25_RS00440
Partner locus tags
DWZ25_RS00435DWZ25_RS00440
Partner old locus tags
DWZ25_00435DWZ25_00440
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_005925704.1Primary protein accession used for annex mappings.
UniProt accessionA8SF25Primary UniProt accession resolved in the annex database.
UniProt IDA8SF25_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWZ25_RS00435Primary locus identifier stored in the genes table.
Old locus tagDWZ25_00435Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QVES01000001.1Sequence record reported by the local genomic context database.
Genomic interval74 900-76 249 nt1 350 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span74 900-76 932 ntGCF_003433905::NZ_QVES01000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003433905::NZ_QVES01000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QVES01000001.1All displayed genes belong to this local TCS context.
Neighborhood span74 900-76 932 nt2 033 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
74 900 nt76 932 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWZ25_RS00435GCF_003433905#DWZ25_RS00435
HKClassicCurrent focus

74 900-76 249 nt · Reverse (-)

Old locus DWZ25_00435RefSeq WP_005925704.1
DWZ25_RS00440GCF_003433905#DWZ25_RS00440
RROmpR

76 246-76 932 nt · Reverse (-)

Old locus DWZ25_00440RefSeq WP_005925707.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1973303Run 6 · HK · 36 sequences
Representative sequenceGCF_000154385#FAEPRAM212_RS10790Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1973303

Simplified PFAM architecture for HKOC_1973303

PFAM domain coverage: 175 / 449 aa (39.0%)

1 aa449 aa
HisKA: 223-288 aaHisKAHATPase_c: 339-447 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[223-288] | HATPase_c[339-447]
  • Domain count: 2
  • Matched identifier: HKOC_1973303
  • Positioned domains: HisKA 223-288 ; HATPase_c 339-447
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154385#FAEPRAM212_RS10790

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 853 · GCF_003433905
AssemblyASM343390v1 · Scaffoldhaploid
Genome composition3 279 664 bp · 55,5% GCFaecalibacterium prausnitzii
Signal transduction countsGenes 54 · HK 25 · RR 27CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key