Gene detail

CDIF27640_RS11955

Histidine kinase, Classic

Clostridioides difficile · GCF_003313585

ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003313585#CDIF27640_RS11955Stable P2CS identifier used across views.
GenomeGCF_003313585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0800914Run 6 · 352 sequences · id 100% · cov 80%
External referencesWP_009890490.1 · A0AB74R1P4 · MIST4 CDIF27640_RS11955RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa686 aa
HisKA: 457-524 aa (68 aa)1HATPase_c: 570-663 aa (94 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:457:0.0000000000000207:524:68:64
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw tokenHATPase_c:570:0.00000000000154:663:98:109
  • Raw architecture: HisKA:457:0.0000000000000207:524:68:64#HATPase_c:570:0.00000000000154:663:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003313585::NZ_CP011848.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2498066-2501014Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF27640_02374RefSeq proteinWP_009890490.1
Context group IDGCF_003313585::NZ_CP011848.1::G00037
Context members
CDIF27640_RS11955CDIF27640_RS11965
Partner locus tags
CDIF27640_RS11955CDIF27640_RS11965
Partner old locus tags
CDIF27640_02374CDIF27640_02375
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009890490.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R1P4Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R1P4_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF27640_RS11955Primary locus identifier stored in the genes table.
Old locus tagCDIF27640_02374Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP011848.1Sequence record reported by the local genomic context database.
Genomic interval2 498 066-2 500 126 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 498 066-2 501 014 ntGCF_003313585::NZ_CP011848.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003313585::NZ_CP011848.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP011848.1All displayed genes belong to this local TCS context.
Neighborhood span2 498 066-2 501 014 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 498 066 nt2 501 014 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF27640_RS11955GCF_003313585#CDIF27640_RS11955
HKClassicCurrent focus

2 498 066-2 500 126 nt · Reverse (-)

Old locus CDIF27640_02374RefSeq WP_009890490.1
CDIF27640_RS11965GCF_003313585#CDIF27640_RS11965
RROmpR

2 500 322-2 501 014 nt · Reverse (-)

Old locus CDIF27640_02375RefSeq WP_004454566.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0800914Run 6 · HK · 352 sequences
Representative sequenceGCF_000003215#QAC_RS0211555Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0800914

Simplified PFAM architecture for HKOC_0800914

PFAM domain coverage: 160 / 686 aa (23.3%)

1 aa686 aa
HisKA: 457-524 aaHisKAHATPase_c: 571-662 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[457-524] | HATPase_c[571-662]
  • Domain count: 2
  • Matched identifier: HKOC_0800914
  • Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0211555

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 352 total members. Page 1 / 8.

GCF_000003215#QAC_RS0211555 (representative)
QAC_RS0211555 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000027105#CDR20291_RS11940
CDR20291_RS11940 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000085225#CD196_RS11645
CD196_RS11645 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000154645#UAA_RS0213435
UAA_RS0213435 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000154665#QAD_RS0211725
QAD_RS0211725 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000154685#AEC_RS0213030
AEC_RS0213030 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000155045#EAA_RS0211465
EAA_RS0211465 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000210455#CD7855_RS11445
CD7855_RS11445 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000211235#CDBI1_RS11540
CDBI1_RS11540 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000450145#QK3_RS11835
QK3_RS11835 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000450765#QO5_RS12200
QO5_RS12200 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000451065#QSC_RS11295
QSC_RS11295 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000451785#QSO_RS10285
QSO_RS10285 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000451885#QU5_RS11360
QU5_RS11360 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000530295#BN174_RS11180
BN174_RS11180 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000531255#BN173_RS11185
BN173_RS11185 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000531785#BN176_RS11320
BN176_RS11320 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_000826625#BN2378_RS00890
BN2378_RS00890 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_001484885#CD26A54R_RS11465
CD26A54R_RS11465 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_001484895#CD26A54S_RS11580
CD26A54S_RS11580 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_001857645#HMPREF3082_RS01175
HMPREF3082_RS01175 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_001971835#BER28_RS11905
BER28_RS11905 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_001972015#BER29_RS11850
BER29_RS11850 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002301945#BGU80_RS03620
BGU80_RS03620 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002302755#BGV00_RS18735
BGV00_RS18735 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002302765#BGV01_RS13085
BGV01_RS13085 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002303165#BGV24_RS16460
BGV24_RS16460 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002335485#NCKUH21_RS11320
NCKUH21_RS11320 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002812585#CWR57_RS11285
CWR57_RS11285 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002891495#AMR93_RS07955
AMR93_RS07955 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002945415#C3W74_RS11960
C3W74_RS11960 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002945515#C3L34_RS12445
C3L34_RS12445 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002945665#C3347_RS11960
C3347_RS11960 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002945755#C3348_RS11965
C3348_RS11965 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002945855#C3350_RS11975
C3350_RS11975 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002945945#C3349_RS11965
C3349_RS11965 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002946035#C3351_RS11970
C3351_RS11970 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002946135#C3352_RS11970
C3352_RS11970 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002946195#C3353_RS11960
C3353_RS11960 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_002954285#AMR92_RS01545
AMR92_RS01545 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003313545#CDIF27638_RS11965
CDIF27638_RS11965 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003313585#CDIF27640_RS11955
CDIF27640_RS11955 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003597795#DA426_RS07950
DA426_RS07950 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003597815#DA430_RS11960
DA430_RS11960 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003597835#DA432_RS11915
DA432_RS11915 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003597895#DA422_RS11725
DA422_RS11725 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003597915#DA436_RS11910
DA436_RS11910 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003625415#C0215_RS01915
C0215_RS01915 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003625425#C0983_RS10600
C0983_RS10600 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4
GCF_003625435#C0984_RS01870
C0984_RS01870 · HK · Classic
RefSeq: WP_009890490.1
UniProt: A0AB74R1P4

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003313585
AssemblyASM331358v1 · Complete Genomehaploid
Genome composition4 229 629 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key