Gene detail

DDG61_RS14895

Histidine kinase, Classic

Clostridioides difficile · GCF_003095695

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003095695#DDG61_RS14895Stable P2CS identifier used across views.
GenomeGCF_003095695Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2071686Run 6 · 257 sequences · id 100% · cov 80%
External referencesWP_003426382.1 · A0A9P4DAK2 · MIST4 DDG61_RS14895RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage218 / 440 aa (49.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
HAMP: 156-222 aa (67 aa)1HisKA: 233-291 aa (59 aa)2HATPase_c: 348-439 aa (92 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
156-222 aa · 67 aa · 15.2% of protein
Raw tokenHAMP:156:0.000000000514:222:70:69
2 HisKA#2
233-291 aa · 59 aa · 13.4% of protein
Raw tokenHisKA:233:0.000000000175:291:59:64
3 HATPase_c#3
348-439 aa · 92 aa · 20.9% of protein
Raw tokenHATPase_c:348:0.00000000968:439:108:109
  • Raw architecture: HAMP:156:0.000000000514:222:70:69#HisKA:233:0.000000000175:291:59:64#HATPase_c:348:0.00000000968:439:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003095695::NZ_CP029152.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3133538-3135557Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDDG61_14895RefSeq proteinWP_003426382.1
Context group IDGCF_003095695::NZ_CP029152.1::G00045
Context members
DDG61_RS14895DDG61_RS14900
Partner locus tags
DDG61_RS14895DDG61_RS14900
Partner old locus tags
DDG61_14895DDG61_14900
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003426382.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DAK2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DAK2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDDG61_RS14895Primary locus identifier stored in the genes table.
Old locus tagDDG61_14895Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP029152.1Sequence record reported by the local genomic context database.
Genomic interval3 133 538-3 134 860 nt1 323 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 133 538-3 135 557 ntGCF_003095695::NZ_CP029152.1::G00045

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003095695::NZ_CP029152.1::G00045

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP029152.1All displayed genes belong to this local TCS context.
Neighborhood span3 133 538-3 135 557 nt2 020 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 133 538 nt3 135 557 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DDG61_RS14895GCF_003095695#DDG61_RS14895
HKClassicCurrent focus

3 133 538-3 134 860 nt · Reverse (-)

Old locus DDG61_14895RefSeq WP_003426382.1
DDG61_RS14900GCF_003095695#DDG61_RS14900
RROmpR

3 134 853-3 135 557 nt · Reverse (-)

Old locus DDG61_14900RefSeq WP_003426384.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2071686Run 6 · HK · 257 sequences
Representative sequenceGCF_000210395#CDM68_RS14020Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c_53 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2071686

Simplified PFAM architecture for HKOC_2071686

PFAM domain coverage: 175 / 440 aa (39.8%)

1 aa440 aa
HAMP: 177-221 aaHAMPHisKA: 235-291 aaHisKAHATPase_c_5: 364-436 aaHATPase_c_5
HAMPHisKAHATPase_c_5
  • Simplified architecture: HAMP + HisKA + HATPase_c_5
  • Raw architecture: HAMP[177-221] | HisKA[235-291] | HATPase_c_5[364-436]
  • Domain count: 3
  • Matched identifier: HKOC_2071686
  • Positioned domains: HAMP 177-221 ; HisKA 235-291 ; HATPase_c_5 364-436
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS14020

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003095695
AssemblyASM309569v1 · Complete Genomehaploid
Genome composition4 289 548 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key