1 HisKA#1
460-527 aa · 68 aa · 9.9% of protein
Raw token
HisKA:460:0.0000000000000219:527:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DDG61_RS12560
Histidine kinase, Classic
Clostridioides difficile · GCF_003095695
ClassHKTypeClassicLength689 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003095695#DDG61_RS12560Stable P2CS identifier used across views.
GenomeGCF_003095695Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length689 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 689 aa (23.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa689 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
573-666 aa · 94 aa · 13.6% of protein
Raw token
HATPase_c:573:0.00000000000104:666:98:109- Raw architecture: HisKA:460:0.0000000000000219:527:68:64#HATPase_c:573:0.00000000000104:666:98:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003095695::NZ_CP029152.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2617297-2620254Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDDG61_12560RefSeq proteinWP_021427464.1
Context group ID
GCF_003095695::NZ_CP029152.1::G00038Context members
DDG61_RS12560DDG61_RS12570
Partner locus tags
DDG61_RS12560DDG61_RS12570
Partner old locus tags
DDG61_12560DDG61_12570
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021427464.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YM89Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YM89_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDDG61_RS12560Primary locus identifier stored in the genes table.
Old locus tagDDG61_12560Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP029152.1Sequence record reported by the local genomic context database.
Genomic interval2 617 297-2 619 366 nt2 070 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 617 297-2 620 254 ntGCF_003095695::NZ_CP029152.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003095695::NZ_CP029152.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP029152.1All displayed genes belong to this local TCS context.
Neighborhood span2 617 297-2 620 254 nt2 958 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 617 297 nt2 620 254 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DDG61_RS12560GCF_003095695#DDG61_RS12560
HKClassicCurrent focus
2 617 297-2 619 366 nt · Reverse (-)
DDG61_RS12570GCF_003095695#DDG61_RS12570
RROmpR
2 619 562-2 620 254 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS11705Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0794068
Simplified PFAM architecture for HKOC_0794068
PFAM domain coverage: 160 / 689 aa (23.2%)
1 aa689 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[460-527] | HATPase_c[574-665]
- Domain count: 2
- Matched identifier: HKOC_0794068
- Positioned domains: HisKA 460-527 ; HATPase_c 574-665
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS11705
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003095695
AssemblyASM309569v1 · Complete Genomehaploid
Genome composition4 289 548 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key