1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw token
HisKA:185:0.000000000201:250:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DDG61_RS09645
Histidine kinase, Classic
Clostridioides difficile · GCF_003095695
ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003095695#DDG61_RS09645Stable P2CS identifier used across views.
GenomeGCF_003095695Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa410 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw token
HATPase_c:296:1.66e-24:408:113:109- Raw architecture: HisKA:185:0.000000000201:250:66:64#HATPase_c:296:1.66e-24:408:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003095695::NZ_CP029152.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1990170-1992063Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDDG61_09645RefSeq proteinWP_003430155.1
Context group ID
GCF_003095695::NZ_CP029152.1::G00027Context members
DDG61_RS09640DDG61_RS09645
Partner locus tags
DDG61_RS09640DDG61_RS09645
Partner old locus tags
DDG61_09640DDG61_09645
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003430155.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YPB2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YPB2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDDG61_RS09645Primary locus identifier stored in the genes table.
Old locus tagDDG61_09645Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP029152.1Sequence record reported by the local genomic context database.
Genomic interval1 990 831-1 992 063 nt1 233 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 990 170-1 992 063 ntGCF_003095695::NZ_CP029152.1::G00027
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003095695::NZ_CP029152.1::G00027Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP029152.1All displayed genes belong to this local TCS context.
Neighborhood span1 990 170-1 992 063 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 990 170 nt1 992 063 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DDG61_RS09640GCF_003095695#DDG61_RS09640
RROmpR
1 990 170-1 990 841 nt · Forward (+)
DDG61_RS09645GCF_003095695#DDG61_RS09645
HKClassicCurrent focus
1 990 831-1 992 063 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS08860Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2354252
Simplified PFAM architecture for HKOC_2354252
PFAM domain coverage: 178 / 410 aa (43.4%)
1 aa410 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[185-250] | HATPase_c[297-408]
- Domain count: 2
- Matched identifier: HKOC_2354252
- Positioned domains: HisKA 185-250 ; HATPase_c 297-408
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS08860
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003095695
AssemblyASM309569v1 · Complete Genomehaploid
Genome composition4 289 548 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key