1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw token
HisKA:182:0.0000000000000118:240:59:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C4E42_RS16650
Histidine kinase, Classic
Clostridioides difficile · GCF_002946535
ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946535#C4E42_RS16650Stable P2CS identifier used across views.
GenomeGCF_002946535Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw token
HATPase_c:293:9.9e-19:391:100:109- Raw architecture: HisKA:182:0.0000000000000118:240:59:64#HATPase_c:293:9.9e-19:391:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002946535::NZ_CP026615.2::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3624286-3626129Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC4E42_10625RefSeq proteinWP_003417468.1
Context group ID
GCF_002946535::NZ_CP026615.2::G00053Context members
C4E42_RS16645C4E42_RS16650
Partner locus tags
C4E42_RS16645C4E42_RS16650
Partner old locus tags
C4E42_10620C4E42_10625
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003417468.1Primary protein accession used for annex mappings.
UniProt accessionD5PZZ6Primary UniProt accession resolved in the annex database.
UniProt IDD5PZZ6_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC4E42_RS16650Primary locus identifier stored in the genes table.
Old locus tagC4E42_10625Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026615.2Sequence record reported by the local genomic context database.
Genomic interval3 624 948-3 626 129 nt1 182 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 624 286-3 626 129 ntGCF_002946535::NZ_CP026615.2::G00053
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002946535::NZ_CP026615.2::G00053Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026615.2All displayed genes belong to this local TCS context.
Neighborhood span3 624 286-3 626 129 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 624 286 nt3 626 129 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C4E42_RS16645GCF_002946535#C4E42_RS16645
RROmpR
3 624 286-3 624 948 nt · Forward (+)
C4E42_RS16650GCF_002946535#C4E42_RS16650
HKClassicCurrent focus
3 624 948-3 626 129 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0202145Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2503303
Simplified PFAM architecture for HKOC_2503303
PFAM domain coverage: 162 / 393 aa (41.2%)
1 aa393 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[179-240] | HATPase_c[292-391]
- Domain count: 2
- Matched identifier: HKOC_2503303
- Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0202145
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002946535
AssemblyASM294653v2 · Complete Genomehaploid
Genome composition4 093 147 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key