Gene detail

C4E42_RS12495

Histidine kinase, Classic

Clostridioides difficile · GCF_002946535

ClassHKTypeClassicLength465 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_002946535#C4E42_RS12495Stable P2CS identifier used across views.
GenomeGCF_002946535Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1772967Run 6 · 262 sequences · id 100% · cov 80%
External referencesWP_029158131.1 · MIST4 C4E42_RS12495RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length465 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 465 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa465 aa
HisKA: 244-308 aa (65 aa)1HATPase_c: 355-463 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
244-308 aa · 65 aa · 14.0% of protein
Raw tokenHisKA:244:0.0000000000023:308:65:64
2 HATPase_c#2
355-463 aa · 109 aa · 23.4% of protein
Raw tokenHATPase_c:355:1.49e-19:463:109:109
  • Raw architecture: HisKA:244:0.0000000000023:308:65:64#HATPase_c:355:1.49e-19:463:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_002946535::NZ_CP026615.2::G00038
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2721461-2722852Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC4E42_06465RefSeq proteinWP_029158131.1
Context group IDGCF_002946535::NZ_CP026615.2::G00038
Context members
C4E42_RS12495
Partner locus tags
C4E42_RS12495
Partner old locus tags
C4E42_06465
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_029158131.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC4E42_RS12495Primary locus identifier stored in the genes table.
Old locus tagC4E42_06465Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026615.2Sequence record reported by the local genomic context database.
Genomic interval2 721 461-2 722 852 nt1 392 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 721 461-2 722 852 ntGCF_002946535::NZ_CP026615.2::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002946535::NZ_CP026615.2::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026615.2All displayed genes belong to this local TCS context.
Neighborhood span2 721 461-2 722 852 nt1 392 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 721 461 nt2 722 852 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

C4E42_RS12495GCF_002946535#C4E42_RS12495
HKClassicCurrent focus

2 721 461-2 722 852 nt · Reverse (-)

Old locus C4E42_06465RefSeq WP_029158131.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1772967Run 6 · HK · 262 sequences
Representative sequenceGCF_000155065#QAE_RS0206615Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1772967

Simplified PFAM architecture for HKOC_1772967

PFAM domain coverage: 174 / 465 aa (37.4%)

1 aa465 aa
HisKA: 244-308 aaHisKAHATPase_c: 355-463 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[244-308] | HATPase_c[355-463]
  • Domain count: 2
  • Matched identifier: HKOC_1772967
  • Positioned domains: HisKA 244-308 ; HATPase_c 355-463
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0206615

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 262 total members. Page 1 / 6.

GCF_000155065#QAE_RS0206615 (representative)
QAE_RS0206615 · HK · Classic
RefSeq: WP_029158131.1
GCF_000164175#HMPREF0220_RS05105
HMPREF0220_RS05105 · HK · Classic
RefSeq: WP_029158131.1
GCF_000164655#HMPREF0219_RS02440
HMPREF0219_RS02440 · HK · Classic
RefSeq: WP_029158131.1
GCF_000210435#CDM120_RS07060
CDM120_RS07060 · HK · Classic
RefSeq: WP_029158131.1
GCF_000499505#BN164_RS05975
BN164_RS05975 · HK · Classic
RefSeq: WP_029158131.1
GCF_000531165#BN166_RS10865
BN166_RS10865 · HK · Classic
RefSeq: WP_029158131.1
GCF_000582865#BN165_RS06125
BN165_RS06125 · HK · Classic
RefSeq: WP_029158131.1
GCF_001050575#BN163_RS06195
BN163_RS06195 · HK · Classic
RefSeq: WP_029158131.1
GCF_001972065#BER35_RS07245
BER35_RS07245 · HK · Classic
RefSeq: WP_029158131.1
GCF_001972115#BER34_RS12635
BER34_RS12635 · HK · Classic
RefSeq: WP_029158131.1
GCF_002301695#BGU20_RS15245
BGU20_RS15245 · HK · Classic
RefSeq: WP_029158131.1
GCF_002302685#BGU93_RS06015
BGU93_RS06015 · HK · Classic
RefSeq: WP_029158131.1
GCF_002303305#BGU53_RS13325
BGU53_RS13325 · HK · Classic
RefSeq: WP_029158131.1
GCF_002352505#V439_RS11300
V439_RS11300 · HK · Classic
RefSeq: WP_029158131.1
GCF_002412385#V438_RS03880
V438_RS03880 · HK · Classic
RefSeq: WP_029158131.1
GCF_002946515#C4E25_RS06695
C4E25_RS06695 · HK · Classic
RefSeq: WP_029158131.1
GCF_002946535#C4E42_RS12495
C4E42_RS12495 · HK · Classic
RefSeq: WP_029158131.1
GCF_002946555#C4E26_RS06695
C4E26_RS06695 · HK · Classic
RefSeq: WP_029158131.1
GCF_003482165#CDIF29020_RS06940
CDIF29020_RS06940 · HK · Classic
RefSeq: WP_029158131.1
GCF_003482365#CDIF29747_RS06695
CDIF29747_RS06695 · HK · Classic
RefSeq: WP_029158131.1
GCF_003697245#EBL91_RS06600
EBL91_RS06600 · HK · Classic
RefSeq: WP_029158131.1
GCF_004318565#E0Q96_RS10720
E0Q96_RS10720 · HK · Classic
RefSeq: WP_029158131.1
GCF_004318785#E0Q93_RS08745
E0Q93_RS08745 · HK · Classic
RefSeq: WP_029158131.1
GCF_008579085#F6C11_RS15530
F6C11_RS15530 · HK · Classic
RefSeq: WP_029158131.1
GCF_009362915#FTB24_RS12250
FTB24_RS12250 · HK · Classic
RefSeq: WP_029158131.1
GCF_012952655#HCN89_RS07595
HCN89_RS07595 · HK · Classic
RefSeq: WP_029158131.1
GCF_015351855#ITI91_RS07085
ITI91_RS07085 · HK · Classic
RefSeq: WP_029158131.1
GCF_015352255#ITJ05_RS07140
ITJ05_RS07140 · HK · Classic
RefSeq: WP_029158131.1
GCF_015732535#CDIF101085_RS06475
CDIF101085_RS06475 · HK · Classic
RefSeq: WP_029158131.1
GCF_016766955#JMW53_RS14920
JMW53_RS14920 · HK · Classic
RefSeq: WP_029158131.1
GCF_016766975#JMW50_RS03660
JMW50_RS03660 · HK · Classic
RefSeq: WP_029158131.1
GCF_016767015#JMW49_RS01820
JMW49_RS01820 · HK · Classic
RefSeq: WP_029158131.1
GCF_016767035#JMW55_RS16695
JMW55_RS16695 · HK · Classic
RefSeq: WP_029158131.1
GCF_016767055#JMW51_RS14055
JMW51_RS14055 · HK · Classic
RefSeq: WP_029158131.1
GCF_016767095#JMW48_RS08390
JMW48_RS08390 · HK · Classic
RefSeq: WP_029158131.1
GCF_016767115#JMW47_RS04870
JMW47_RS04870 · HK · Classic
RefSeq: WP_029158131.1
GCF_016767135#JMW46_RS16130
JMW46_RS16130 · HK · Classic
RefSeq: WP_029158131.1
GCF_017592625#J5O10_RS06550
J5O10_RS06550 · HK · Classic
RefSeq: WP_029158131.1
GCF_018603395#KK111_RS06800
KK111_RS06800 · HK · Classic
RefSeq: WP_029158131.1
GCF_018603455#KK110_RS06795
KK110_RS06795 · HK · Classic
RefSeq: WP_029158131.1
GCF_018603475#KK112_RS06785
KK112_RS06785 · HK · Classic
RefSeq: WP_029158131.1
GCF_018884725#E1H40_RS06520
E1H40_RS06520 · HK · Classic
RefSeq: WP_029158131.1
GCF_019427665#K1N48_RS15390
K1N48_RS15390 · HK · Classic
RefSeq: WP_029158131.1
GCF_019427725#K1N54_RS06190
K1N54_RS06190 · HK · Classic
RefSeq: WP_029158131.1
GCF_019931025#K8P06_RS17225
K8P06_RS17225 · HK · Classic
RefSeq: WP_029158131.1
GCF_020297505#LA365_RS11785
LA365_RS11785 · HK · Classic
RefSeq: WP_029158131.1
GCF_021283625#LWE91_RS13165
LWE91_RS13165 · HK · Classic
RefSeq: WP_029158131.1
GCF_021283665#LWF03_RS11755
LWF03_RS11755 · HK · Classic
RefSeq: WP_029158131.1
GCF_021283685#LWE71_RS15275
LWE71_RS15275 · HK · Classic
RefSeq: WP_029158131.1
GCF_021283745#LWE78_RS12505
LWE78_RS12505 · HK · Classic
RefSeq: WP_029158131.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002946535
AssemblyASM294653v2 · Complete Genomehaploid
Genome composition4 093 147 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key