1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw token
HAMP:84:0.000000527:152:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C4E25_RS02780
Histidine kinase, Classic
Clostridioides difficile · GCF_002946515
ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946515#C4E25_RS02780Stable P2CS identifier used across views.
GenomeGCF_002946515Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
Domain-by-domain annotation3 items
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw token
HisKA:164:0.0000000445:217:54:643 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw token
HATPase_c:278:1.65e-20:382:106:109- Raw architecture: HAMP:84:0.000000527:152:70:69#HisKA:164:0.0000000445:217:54:64#HATPase_c:278:1.65e-20:382:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002946515::NZ_CP026613.2::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span512358-514180Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC4E25_14240RefSeq proteinWP_003417817.1
Context group ID
GCF_002946515::NZ_CP026613.2::G00004Context members
C4E25_RS02780C4E25_RS02785
Partner locus tags
C4E25_RS02780C4E25_RS02785
Partner old locus tags
C4E25_14240C4E25_14245
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003417817.1Primary protein accession used for annex mappings.
UniProt accessionD5Q091Primary UniProt accession resolved in the annex database.
UniProt IDD5Q091_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC4E25_RS02780Primary locus identifier stored in the genes table.
Old locus tagC4E25_14240Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026613.2Sequence record reported by the local genomic context database.
Genomic interval512 358-513 518 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span512 358-514 180 ntGCF_002946515::NZ_CP026613.2::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002946515::NZ_CP026613.2::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026613.2All displayed genes belong to this local TCS context.
Neighborhood span512 358-514 180 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
512 358 nt514 180 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C4E25_RS02780GCF_002946515#C4E25_RS02780
HKClassicCurrent focus
512 358-513 518 nt · Reverse (-)
C4E25_RS02785GCF_002946515#C4E25_RS02785
RROmpR
513 506-514 180 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0202410Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2557654
Simplified PFAM architecture for HKOC_2557654
PFAM domain coverage: 219 / 386 aa (56.7%)
1 aa386 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
- Domain count: 3
- Matched identifier: HKOC_2557654
- Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0202410
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002946515
AssemblyASM294651v2 · Complete Genomehaploid
Genome composition4 093 143 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key