1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw token
HisKA:309:0.0000000000000134:375:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C3353_RS12060
Histidine kinase, Classic
Clostridioides difficile · GCF_002946195
ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946195#C3353_RS12060Stable P2CS identifier used across views.
GenomeGCF_002946195Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa530 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw token
HATPase_c:428:0.0000000388:513:90:109- Raw architecture: HisKA:309:0.0000000000000134:375:67:64#HATPase_c:428:0.0000000388:513:90:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002946195::NZ_CP026599.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2517607-2519884Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3353_12060RefSeq proteinWP_009893576.1
Context group ID
GCF_002946195::NZ_CP026599.1::G00038Context members
C3353_RS12055C3353_RS12060
Partner locus tags
C3353_RS12055C3353_RS12060
Partner old locus tags
C3353_12055C3353_12060
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009893576.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R630Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R630_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC3353_RS12060Primary locus identifier stored in the genes table.
Old locus tagC3353_12060Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026599.1Sequence record reported by the local genomic context database.
Genomic interval2 518 292-2 519 884 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 517 607-2 519 884 ntGCF_002946195::NZ_CP026599.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002946195::NZ_CP026599.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026599.1All displayed genes belong to this local TCS context.
Neighborhood span2 517 607-2 519 884 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 517 607 nt2 519 884 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C3353_RS12055GCF_002946195#C3353_RS12055
RROmpR
2 517 607-2 518 323 nt · Forward (+)
C3353_RS12060GCF_002946195#C3353_RS12060
HKClassicCurrent focus
2 518 292-2 519 884 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0211650Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1355490
Simplified PFAM architecture for HKOC_1355490
PFAM domain coverage: 191 / 530 aa (36.0%)
1 aa530 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
- Domain count: 3
- Matched identifier: HKOC_1355490
- Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0211650
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002946195
AssemblyASM294619v1 · Complete Genomehaploid
Genome composition4 119 929 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key