Gene detail

C3353_RS09375

Histidine kinase, Classic

Clostridioides difficile · GCF_002946195

ClassHKTypeClassicLength664 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946195#C3353_RS09375Stable P2CS identifier used across views.
GenomeGCF_002946195Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860209Run 6 · 349 sequences · id 100% · cov 80%
External referencesWP_009889695.1 · A0A0H3N2M2 · MIST4 C3353_RS09375RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length664 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 664 aa (58.1%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa664 aa
SBP_bac_3: 58-278 aa (221 aa)1HisKA: 446-508 aa (63 aa)2HATPase_c: 557-658 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
58-278 aa · 221 aa · 33.3% of protein
Raw tokenSBP_bac_3:58:1.72e-41:278:230:224
2 HisKA#2
446-508 aa · 63 aa · 9.5% of protein
Raw tokenHisKA:446:0.0000000000000409:508:63:64
3 HATPase_c#3
557-658 aa · 102 aa · 15.4% of protein
Raw tokenHATPase_c:557:2.12e-23:658:103:109
  • Raw architecture: SBP_bac_3:58:1.72e-41:278:230:224#HisKA:446:0.0000000000000409:508:63:64#HATPase_c:557:2.12e-23:658:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002946195::NZ_CP026599.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1934349-1937665Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3353_09375RefSeq proteinWP_009889695.1
Context group IDGCF_002946195::NZ_CP026599.1::G00029
Context members
C3353_RS09375C3353_RS09380
Partner locus tags
C3353_RS09375C3353_RS09380
Partner old locus tags
C3353_09375C3353_09380
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889695.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N2M2Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N2M2_CLODCDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3353_RS09375Primary locus identifier stored in the genes table.
Old locus tagC3353_09375Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026599.1Sequence record reported by the local genomic context database.
Genomic interval1 934 349-1 936 343 nt1 995 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 934 349-1 937 665 ntGCF_002946195::NZ_CP026599.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002946195::NZ_CP026599.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026599.1All displayed genes belong to this local TCS context.
Neighborhood span1 934 349-1 937 665 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 934 349 nt1 937 665 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3353_RS09375GCF_002946195#C3353_RS09375
HKClassicCurrent focus

1 934 349-1 936 343 nt · Forward (+)

Old locus C3353_09375RefSeq WP_009889695.1
C3353_RS09380GCF_002946195#C3353_RS09380
RRNtrC

1 936 343-1 937 665 nt · Forward (+)

Old locus C3353_09380RefSeq WP_009893260.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860209Run 6 · HK · 349 sequences
Representative sequenceGCF_000003215#QAC_RS0208985Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860209

Simplified PFAM architecture for HKOC_0860209

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860209
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0208985

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 349 total members. Page 1 / 7.

GCF_000003215#QAC_RS0208985 (representative)
QAC_RS0208985 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000027105#CDR20291_RS08945
CDR20291_RS08945 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000085225#CD196_RS09105
CD196_RS09105 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000154645#UAA_RS0210865
UAA_RS0210865 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000154665#QAD_RS0209155
QAD_RS0209155 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000154685#AEC_RS0210465
AEC_RS0210465 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000155045#EAA_RS0208895
EAA_RS0208895 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000210455#CD7855_RS08935
CD7855_RS08935 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000211235#CDBI1_RS09025
CDBI1_RS09025 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000450145#QK3_RS09280
QK3_RS09280 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000450765#QO5_RS09530
QO5_RS09530 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000451065#QSC_RS08755
QSC_RS08755 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000451785#QSO_RS07750
QSO_RS07750 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000451885#QU5_RS08820
QU5_RS08820 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000530295#BN174_RS08640
BN174_RS08640 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000531255#BN173_RS08645
BN173_RS08645 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_000826625#BN2378_RS17550
BN2378_RS17550 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_001484885#CD26A54R_RS08905
CD26A54R_RS08905 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_001484895#CD26A54S_RS08920
CD26A54S_RS08920 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_001857645#HMPREF3082_RS12360
HMPREF3082_RS12360 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_001971835#BER28_RS09345
BER28_RS09345 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_001972015#BER29_RS09290
BER29_RS09290 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002301945#BGU80_RS08775
BGU80_RS08775 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002302755#BGV00_RS10470
BGV00_RS10470 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002302765#BGV01_RS04785
BGV01_RS04785 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002303165#BGV24_RS04535
BGV24_RS04535 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002335485#NCKUH21_RS08760
NCKUH21_RS08760 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002812585#CWR57_RS08700
CWR57_RS08700 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002891495#AMR93_RS16200
AMR93_RS16200 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002945415#C3W74_RS09375
C3W74_RS09375 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002945515#C3L34_RS09360
C3L34_RS09360 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002945665#C3347_RS09375
C3347_RS09375 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002945755#C3348_RS09380
C3348_RS09380 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002945855#C3350_RS09390
C3350_RS09390 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002945945#C3349_RS09380
C3349_RS09380 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002946035#C3351_RS09385
C3351_RS09385 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002946135#C3352_RS09385
C3352_RS09385 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002946195#C3353_RS09375
C3353_RS09375 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_002954285#AMR92_RS02480
AMR92_RS02480 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003313545#CDIF27638_RS09375
CDIF27638_RS09375 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003313585#CDIF27640_RS09365
CDIF27640_RS09365 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003482035#CDIF28196_RS09380
CDIF28196_RS09380 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003597795#DA426_RS10540
DA426_RS10540 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003597815#DA430_RS09370
DA430_RS09370 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003597835#DA432_RS09325
DA432_RS09325 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003597895#DA422_RS09270
DA422_RS09270 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003597915#DA436_RS09320
DA436_RS09320 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003625415#C0215_RS04675
C0215_RS04675 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003625425#C0983_RS01235
C0983_RS01235 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2
GCF_003625435#C0984_RS04300
C0984_RS04300 · HK · Classic
RefSeq: WP_009889695.1
UniProt: A0A0H3N2M2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002946195
AssemblyASM294619v1 · Complete Genomehaploid
Genome composition4 119 929 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key