1 HisKA#1
89-151 aa · 63 aa · 20.5% of protein
Raw token
HisKA:89:0.0000000554:151:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C3353_RS02260
Histidine kinase, Classic
Clostridioides difficile · GCF_002946195
ClassHKTypeClassicLength307 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946195#C3353_RS02260Stable P2CS identifier used across views.
GenomeGCF_002946195Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length307 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 307 aa (55.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa307 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
199-306 aa · 108 aa · 35.2% of protein
Raw token
HATPase_c:199:8.88e-30:306:108:109- Raw architecture: HisKA:89:0.0000000554:151:63:64#HATPase_c:199:8.88e-30:306:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002946195::NZ_CP026599.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span401006-402632Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3353_02260RefSeq proteinWP_009888178.1
Context group ID
GCF_002946195::NZ_CP026599.1::G00002Context members
C3353_RS02260C3353_RS02265
Partner locus tags
C3353_RS02260C3353_RS02265
Partner old locus tags
C3353_02260C3353_02265
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009888178.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MYW5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MYW5_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC3353_RS02260Primary locus identifier stored in the genes table.
Old locus tagC3353_02260Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026599.1Sequence record reported by the local genomic context database.
Genomic interval401 006-401 929 nt924 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span401 006-402 632 ntGCF_002946195::NZ_CP026599.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002946195::NZ_CP026599.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026599.1All displayed genes belong to this local TCS context.
Neighborhood span401 006-402 632 nt1 627 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
401 006 nt402 632 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C3353_RS02260GCF_002946195#C3353_RS02260
HKClassicCurrent focus
401 006-401 929 nt · Reverse (-)
C3353_RS02265GCF_002946195#C3353_RS02265
RROmpR
401 931-402 632 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0202000Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2880535
Simplified PFAM architecture for HKOC_2880535
PFAM domain coverage: 172 / 307 aa (56.0%)
1 aa307 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[88-151] | HATPase_c[199-306]
- Domain count: 2
- Matched identifier: HKOC_2880535
- Positioned domains: HisKA 88-151 ; HATPase_c 199-306
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0202000
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002946195
AssemblyASM294619v1 · Complete Genomehaploid
Genome composition4 119 929 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key