1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw token
HisKA:168:0.000000000000741:234:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C3352_RS18620
Histidine kinase, Classic
Clostridioides difficile · GCF_002946135
ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946135#C3352_RS18620Stable P2CS identifier used across views.
GenomeGCF_002946135Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw token
HATPase_c:280:1.27e-26:388:110:109- Raw architecture: HisKA:168:0.000000000000741:234:67:64#HATPase_c:280:1.27e-26:388:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002946135::NZ_CP026598.1::G00058
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4013592-4015455Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3352_18620RefSeq proteinWP_021397485.1
Context group ID
GCF_002946135::NZ_CP026598.1::G00058Context members
C3352_RS18620C3352_RS18625
Partner locus tags
C3352_RS18620C3352_RS18625
Partner old locus tags
C3352_18620C3352_18625
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021397485.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC3352_RS18620Primary locus identifier stored in the genes table.
Old locus tagC3352_18620Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026598.1Sequence record reported by the local genomic context database.
Genomic interval4 013 592-4 014 533 nt942 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 013 592-4 015 455 ntGCF_002946135::NZ_CP026598.1::G00058
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002946135::NZ_CP026598.1::G00058Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026598.1All displayed genes belong to this local TCS context.
Neighborhood span4 013 592-4 015 455 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 013 592 nt4 015 455 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C3352_RS18620GCF_002946135#C3352_RS18620
HKClassicCurrent focus
4 013 592-4 014 533 nt · Reverse (-)
C3352_RS18625GCF_002946135#C3352_RS18625
RROmpR
4 014 763-4 015 455 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0218365Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2503238
Simplified PFAM architecture for HKOC_2503238
PFAM domain coverage: 175 / 393 aa (44.5%)
1 aa393 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[168-233] | HATPase_c[281-389]
- Domain count: 2
- Matched identifier: HKOC_2503238
- Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0218365
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002946135
AssemblyASM294613v1 · Complete Genomehaploid
Genome composition4 120 065 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key