Gene detail

C3349_RS13180

Histidine kinase, Classic

Clostridioides difficile · GCF_002945945

ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945945#C3349_RS13180Stable P2CS identifier used across views.
GenomeGCF_002945945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2113046Run 6 · 360 sequences · id 100% · cov 80%
External referencesWP_009893643.1 · A0A0H3N9E9 · MIST4 C3349_RS13180RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa436 aa
HisKA: 218-278 aa (61 aa)1HATPase_c: 334-433 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw tokenHisKA:218:0.0000000000608:278:61:64
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw tokenHATPase_c:334:4.89e-25:433:100:109
  • Raw architecture: HisKA:218:0.0000000000608:278:61:64#HATPase_c:334:4.89e-25:433:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945945::NZ_CP026596.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2766316-2768327Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3349_13180RefSeq proteinWP_009893643.1
Context group IDGCF_002945945::NZ_CP026596.1::G00040
Context members
C3349_RS13180C3349_RS13185
Partner locus tags
C3349_RS13180C3349_RS13185
Partner old locus tags
C3349_13180C3349_13185
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893643.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N9E9Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N9E9_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3349_RS13180Primary locus identifier stored in the genes table.
Old locus tagC3349_13180Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026596.1Sequence record reported by the local genomic context database.
Genomic interval2 766 316-2 767 626 nt1 311 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 766 316-2 768 327 ntGCF_002945945::NZ_CP026596.1::G00040

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945945::NZ_CP026596.1::G00040

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026596.1All displayed genes belong to this local TCS context.
Neighborhood span2 766 316-2 768 327 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 766 316 nt2 768 327 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3349_RS13180GCF_002945945#C3349_RS13180
HKClassicCurrent focus

2 766 316-2 767 626 nt · Reverse (-)

Old locus C3349_13180RefSeq WP_009893643.1
C3349_RS13185GCF_002945945#C3349_RS13185
RROmpR

2 767 620-2 768 327 nt · Reverse (-)

Old locus C3349_13185RefSeq WP_009890737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2113046Run 6 · HK · 360 sequences
Representative sequenceGCF_000003215#QAC_RS0212785Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2113046

Simplified PFAM architecture for HKOC_2113046

PFAM domain coverage: 166 / 436 aa (38.1%)

1 aa436 aa
HisKA: 217-278 aaHisKAHATPase_c: 330-433 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[217-278] | HATPase_c[330-433]
  • Domain count: 2
  • Matched identifier: HKOC_2113046
  • Positioned domains: HisKA 217-278 ; HATPase_c 330-433
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0212785

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945945
AssemblyASM294594v1 · Complete Genomehaploid
Genome composition4 119 720 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key