Gene detail

C3349_RS08775

Histidine kinase, Classic

Clostridioides difficile · GCF_002945945

ClassHKTypeClassicLength360 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945945#C3349_RS08775Stable P2CS identifier used across views.
GenomeGCF_002945945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2746944Run 6 · 785 sequences · id 100% · cov 80%
External referencesWP_012816161.1 · A0A0H3N707 · MIST4 C3349_RS08775RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length360 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 360 aa (44.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa360 aa
HisKA: 135-198 aa (64 aa)1HATPase_c: 248-344 aa (97 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
135-198 aa · 64 aa · 17.8% of protein
Raw tokenHisKA:135:0.000000000000365:198:64:64
2 HATPase_c#2
248-344 aa · 97 aa · 26.9% of protein
Raw tokenHATPase_c:248:2.05e-21:344:97:109
  • Raw architecture: HisKA:135:0.000000000000365:198:64:64#HATPase_c:248:2.05e-21:344:97:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945945::NZ_CP026596.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1807881-1809714Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3349_08775RefSeq proteinWP_012816161.1
Context group IDGCF_002945945::NZ_CP026596.1::G00026
Context members
C3349_RS08770C3349_RS08775
Partner locus tags
C3349_RS08770C3349_RS08775
Partner old locus tags
C3349_08770C3349_08775
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012816161.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N707Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N707_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3349_RS08775Primary locus identifier stored in the genes table.
Old locus tagC3349_08775Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026596.1Sequence record reported by the local genomic context database.
Genomic interval1 808 632-1 809 714 nt1 083 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 807 881-1 809 714 ntGCF_002945945::NZ_CP026596.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945945::NZ_CP026596.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026596.1All displayed genes belong to this local TCS context.
Neighborhood span1 807 881-1 809 714 nt1 834 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 807 881 nt1 809 714 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3349_RS08770GCF_002945945#C3349_RS08770
RROmpR

1 807 881-1 808 582 nt · Forward (+)

Old locus C3349_08770RefSeq WP_021419359.1
C3349_RS08775GCF_002945945#C3349_RS08775
HKClassicCurrent focus

1 808 632-1 809 714 nt · Forward (+)

Old locus C3349_08775RefSeq WP_012816161.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2746944Run 6 · HK · 785 sequences
Representative sequenceGCF_000003215#QAC_RS0208405Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2746944

Simplified PFAM architecture for HKOC_2746944

PFAM domain coverage: 161 / 360 aa (44.7%)

1 aa360 aa
HisKA: 136-198 aaHisKAHATPase_c: 248-345 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[136-198] | HATPase_c[248-345]
  • Domain count: 2
  • Matched identifier: HKOC_2746944
  • Positioned domains: HisKA 136-198 ; HATPase_c 248-345
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0208405

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 785 total members. Page 1 / 16.

GCF_000003215#QAC_RS0208405 (representative)
QAC_RS0208405 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000027105#CDR20291_RS08360
CDR20291_RS08360 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000085225#CD196_RS08515
CD196_RS08515 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000154645#UAA_RS0210280
UAA_RS0210280 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000154665#QAD_RS0208580
QAD_RS0208580 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000154685#AEC_RS0209885
AEC_RS0209885 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000155045#EAA_RS0208315
EAA_RS0208315 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000210455#CD7855_RS08355
CD7855_RS08355 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000211235#CDBI1_RS08445
CDBI1_RS08445 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000448745#QC1_RS08755
QC1_RS08755 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000448825#QAO_RS07915
QAO_RS07915 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000448845#QAQ_RS08110
QAQ_RS08110 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000448865#QAS_RS08320
QAS_RS08320 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000449205#QMQ_RS08410
QMQ_RS08410 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000449225#QCY_RS08400
QCY_RS08400 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000449245#QEA_RS08660
QEA_RS08660 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000449365#QEQ_RS08285
QEQ_RS08285 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000449805#QGY_RS08010
QGY_RS08010 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000449825#QI3_RS08475
QI3_RS08475 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000449925#QIE_RS08340
QIE_RS08340 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000449985#QIK_RS09150
QIK_RS09150 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450045#QIS_RS08665
QIS_RS08665 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450125#QK1_RS10300
QK1_RS10300 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450305#QKK_RS08830
QKK_RS08830 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450345#QKO_RS08345
QKO_RS08345 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450385#QKS_RS08160
QKS_RS08160 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450425#QKW_RS08505
QKW_RS08505 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450505#QM5_RS08130
QM5_RS08130 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450525#QM7_RS08040
QM7_RS08040 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450585#QMC_RS08060
QMC_RS08060 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450645#QSA_RS08925
QSA_RS08925 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450705#QMW_RS08635
QMW_RS08635 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450765#QO5_RS08940
QO5_RS08940 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450845#QOI_RS07960
QOI_RS07960 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450905#QQI_RS07450
QQI_RS07450 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000450965#QQQ_RS08235
QQQ_RS08235 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451065#QSC_RS08175
QSC_RS08175 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451145#QQ1_RS07615
QQ1_RS07615 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451205#QE5_RS08485
QE5_RS08485 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451265#QOW_RS08250
QOW_RS08250 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451565#QQO_RS08320
QQO_RS08320 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451605#QQU_RS07870
QQU_RS07870 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451665#QS3_RS08220
QS3_RS08220 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451785#QSO_RS07170
QSO_RS07170 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451885#QU5_RS08240
QU5_RS08240 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451905#QU7_RS08490
QU7_RS08490 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451925#QU9_RS08325
QU9_RS08325 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000451985#QUE_RS10885
QUE_RS10885 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000452045#QUM_RS08600
QUM_RS08600 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707
GCF_000452085#QUU_RS08020
QUU_RS08020 · HK · Classic
RefSeq: WP_012816161.1
UniProt: A0A0H3N707

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945945
AssemblyASM294594v1 · Complete Genomehaploid
Genome composition4 119 720 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key