Gene detail

C3349_RS05190

Histidine kinase, Classic

Clostridioides difficile · GCF_002945945

ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945945#C3349_RS05190Stable P2CS identifier used across views.
GenomeGCF_002945945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2328063Run 6 · 337 sequences · id 100% · cov 80%
External referencesWP_009888761.1 · A0A0H3N0H7 · MIST4 C3349_RS05190RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 413 aa (40.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa413 aa
HisKA: 195-255 aa (61 aa)1HATPase_c: 302-407 aa (106 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
195-255 aa · 61 aa · 14.8% of protein
Raw tokenHisKA:195:0.000000000000848:255:61:64
2 HATPase_c#2
302-407 aa · 106 aa · 25.7% of protein
Raw tokenHATPase_c:302:1.98e-26:407:107:109
  • Raw architecture: HisKA:195:0.000000000000848:255:61:64#HATPase_c:302:1.98e-26:407:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945945::NZ_CP026596.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1062625-1064560Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3349_05190RefSeq proteinWP_009888761.1
Context group IDGCF_002945945::NZ_CP026596.1::G00016
Context members
C3349_RS05185C3349_RS05190
Partner locus tags
C3349_RS05185C3349_RS05190
Partner old locus tags
C3349_05185C3349_05190
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009888761.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N0H7Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N0H7_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3349_RS05190Primary locus identifier stored in the genes table.
Old locus tagC3349_05190Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026596.1Sequence record reported by the local genomic context database.
Genomic interval1 063 319-1 064 560 nt1 242 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 062 625-1 064 560 ntGCF_002945945::NZ_CP026596.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945945::NZ_CP026596.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026596.1All displayed genes belong to this local TCS context.
Neighborhood span1 062 625-1 064 560 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 062 625 nt1 064 560 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3349_RS05185GCF_002945945#C3349_RS05185
RROmpR

1 062 625-1 063 308 nt · Forward (+)

Old locus C3349_05185RefSeq WP_003418728.1
C3349_RS05190GCF_002945945#C3349_RS05190
HKClassicCurrent focus

1 063 319-1 064 560 nt · Forward (+)

Old locus C3349_05190RefSeq WP_009888761.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2328063Run 6 · HK · 337 sequences
Representative sequenceGCF_000003215#QAC_RS0204855Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2328063

Simplified PFAM architecture for HKOC_2328063

PFAM domain coverage: 172 / 413 aa (41.6%)

1 aa413 aa
HisKA: 193-255 aaHisKAHATPase_c: 302-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[193-255] | HATPase_c[302-410]
  • Domain count: 2
  • Matched identifier: HKOC_2328063
  • Positioned domains: HisKA 193-255 ; HATPase_c 302-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0204855

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945945
AssemblyASM294594v1 · Complete Genomehaploid
Genome composition4 119 720 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key