Gene detail

C3349_RS04605

Histidine kinase, Classic

Clostridioides difficile · GCF_002945945

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945945#C3349_RS04605Stable P2CS identifier used across views.
GenomeGCF_002945945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876366Run 6 · 342 sequences · id 100% · cov 80%
External referencesWP_012816055.1 · A0A0H3N4S2 · MIST4 C3349_RS04605RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for C3349_RS04605
Domain-by-domain annotation2 items
1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw tokenHisKA:94:0.000000109:156:63:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:2.61e-30:310:107:109
  • Raw architecture: HisKA:94:0.000000109:156:63:64#HATPase_c:204:2.61e-30:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945945::NZ_CP026596.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span934586-936210Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3349_04605RefSeq proteinWP_012816055.1
Context group IDGCF_002945945::NZ_CP026596.1::G00015
Context members
C3349_RS04600C3349_RS04605
Partner locus tags
C3349_RS04600C3349_RS04605
Partner old locus tags
C3349_04600C3349_04605
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012816055.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N4S2Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N4S2_CLODCDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3349_RS04605Primary locus identifier stored in the genes table.
Old locus tagC3349_04605Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026596.1Sequence record reported by the local genomic context database.
Genomic interval935 275-936 210 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span934 586-936 210 ntGCF_002945945::NZ_CP026596.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945945::NZ_CP026596.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026596.1All displayed genes belong to this local TCS context.
Neighborhood span934 586-936 210 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
934 586 nt936 210 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3349_RS04600GCF_002945945#C3349_RS04600
RROmpR

934 586-935 278 nt · Forward (+)

Old locus C3349_04600RefSeq WP_009888625.1
C3349_RS04605GCF_002945945#C3349_RS04605
HKClassicCurrent focus

935 275-936 210 nt · Forward (+)

Old locus C3349_04605RefSeq WP_012816055.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876366Run 6 · HK · 342 sequences
Representative sequenceGCF_000003215#QAC_RS0204275Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876366

Simplified PFAM architecture for HKOC_2876366

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876366
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0204275

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945945
AssemblyASM294594v1 · Complete Genomehaploid
Genome composition4 119 720 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key