Gene detail

C3348_RS18845

Histidine kinase, Classic

Clostridioides difficile · GCF_002945755

ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945755#C3348_RS18845Stable P2CS identifier used across views.
GenomeGCF_002945755Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2857935Run 6 · 352 sequences · id 100% · cov 80%
External referencesWP_009892170.1 · A0A0H3NGL7 · MIST4 C3348_RS18845RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa329 aa
HisKA: 117-177 aa (61 aa)1HATPase_c: 222-328 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw tokenHisKA:117:0.000000000148:177:61:64
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw tokenHATPase_c:222:4.73e-24:328:108:109
  • Raw architecture: HisKA:117:0.000000000148:177:61:64#HATPase_c:222:4.73e-24:328:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945755::NZ_CP026594.1::G00059
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4051784-4053446Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3348_18845RefSeq proteinWP_009892170.1
Context group IDGCF_002945755::NZ_CP026594.1::G00059
Context members
C3348_RS18845C3348_RS18850
Partner locus tags
C3348_RS18845C3348_RS18850
Partner old locus tags
C3348_18845C3348_18850
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009892170.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NGL7Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NGL7_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3348_RS18845Primary locus identifier stored in the genes table.
Old locus tagC3348_18845Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026594.1Sequence record reported by the local genomic context database.
Genomic interval4 051 784-4 052 773 nt990 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 051 784-4 053 446 ntGCF_002945755::NZ_CP026594.1::G00059

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945755::NZ_CP026594.1::G00059

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026594.1All displayed genes belong to this local TCS context.
Neighborhood span4 051 784-4 053 446 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 051 784 nt4 053 446 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3348_RS18845GCF_002945755#C3348_RS18845
HKClassicCurrent focus

4 051 784-4 052 773 nt · Reverse (-)

Old locus C3348_18845RefSeq WP_009892170.1
C3348_RS18850GCF_002945755#C3348_RS18850
RROmpR

4 052 760-4 053 446 nt · Reverse (-)

Old locus C3348_18850RefSeq WP_003434895.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2857935Run 6 · HK · 352 sequences
Representative sequenceGCF_000003215#QAC_RS0218295Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2857935

Simplified PFAM architecture for HKOC_2857935

PFAM domain coverage: 169 / 329 aa (51.4%)

1 aa329 aa
HisKA: 116-177 aaHisKAHATPase_c: 222-328 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[116-177] | HATPase_c[222-328]
  • Domain count: 2
  • Matched identifier: HKOC_2857935
  • Positioned domains: HisKA 116-177 ; HATPase_c 222-328
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0218295

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 352 total members. Page 1 / 8.

GCF_000003215#QAC_RS0218295 (representative)
QAC_RS0218295 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000027105#CDR20291_RS18405
CDR20291_RS18405 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000085225#CD196_RS18145
CD196_RS18145 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000154645#UAA_RS0219910
UAA_RS0219910 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000154665#QAD_RS0218085
QAD_RS0218085 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000154685#AEC_RS0219765
AEC_RS0219765 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000155045#EAA_RS0217890
EAA_RS0217890 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000210455#CD7855_RS18300
CD7855_RS18300 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000211235#CDBI1_RS17995
CDBI1_RS17995 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000450145#QK3_RS18170
QK3_RS18170 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000450765#QO5_RS18690
QO5_RS18690 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000451065#QSC_RS17710
QSC_RS17710 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000451785#QSO_RS17960
QSO_RS17960 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000451885#QU5_RS18055
QU5_RS18055 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000452005#QUI_RS00760
QUI_RS00760 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000530295#BN174_RS17360
BN174_RS17360 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000531255#BN173_RS17335
BN173_RS17335 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_000826625#BN2378_RS07745
BN2378_RS07745 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_001484885#CD26A54R_RS18245
CD26A54R_RS18245 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_001484895#CD26A54S_RS18360
CD26A54S_RS18360 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_001857645#HMPREF3082_RS07220
HMPREF3082_RS07220 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_001971835#BER28_RS18745
BER28_RS18745 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_001972015#BER29_RS18675
BER29_RS18675 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002301945#BGU80_RS12975
BGU80_RS12975 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002302765#BGV01_RS16215
BGV01_RS16215 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002303105#BGV21_RS06520
BGV21_RS06520 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002303165#BGV24_RS06050
BGV24_RS06050 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002335485#NCKUH21_RS17830
NCKUH21_RS17830 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002812585#CWR57_RS18260
CWR57_RS18260 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002945415#C3W74_RS18550
C3W74_RS18550 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002945515#C3L34_RS19030
C3L34_RS19030 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002945665#C3347_RS18545
C3347_RS18545 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002945755#C3348_RS18845
C3348_RS18845 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002945855#C3350_RS18560
C3350_RS18560 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002945945#C3349_RS18550
C3349_RS18550 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002946035#C3351_RS18560
C3351_RS18560 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002946135#C3352_RS18555
C3352_RS18555 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002946195#C3353_RS18545
C3353_RS18545 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_002954285#AMR92_RS17900
AMR92_RS17900 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003313545#CDIF27638_RS19165
CDIF27638_RS19165 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003313585#CDIF27640_RS19155
CDIF27640_RS19155 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003482035#CDIF28196_RS19080
CDIF28196_RS19080 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003597795#DA426_RS00755
DA426_RS00755 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003597815#DA430_RS18845
DA430_RS18845 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003597835#DA432_RS18595
DA432_RS18595 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003597895#DA422_RS18915
DA422_RS18915 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003597915#DA436_RS18875
DA436_RS18875 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003625415#C0215_RS17915
C0215_RS17915 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003625425#C0983_RS15405
C0983_RS15405 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7
GCF_003625435#C0984_RS17935
C0984_RS17935 · HK · Classic
RefSeq: WP_009892170.1
UniProt: A0A0H3NGL7

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945755
AssemblyASM294575v1 · Complete Genomehaploid
Genome composition4 177 956 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key