Gene detail

C3348_RS11075

Histidine kinase, Classic

Clostridioides difficile · GCF_002945755

ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945755#C3348_RS11075Stable P2CS identifier used across views.
GenomeGCF_002945755Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2215984Run 6 · 335 sequences · id 100% · cov 80%
External referencesWP_009890242.1 · A0A0H3N4E5 · MIST4 C3348_RS11075RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa425 aa
HisKA: 196-260 aa (65 aa)1HATPase_c: 307-424 aa (118 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw tokenHisKA:196:0.0000000000151:260:65:64
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw tokenHATPase_c:307:2.03e-18:424:119:109
  • Raw architecture: HisKA:196:0.0000000000151:260:65:64#HATPase_c:307:2.03e-18:424:119:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945755::NZ_CP026594.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2291509-2293438Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3348_11075RefSeq proteinWP_009890242.1
Context group IDGCF_002945755::NZ_CP026594.1::G00036
Context members
C3348_RS11075C3348_RS11080
Partner locus tags
C3348_RS11075C3348_RS11080
Partner old locus tags
C3348_11075C3348_11080
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009890242.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N4E5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N4E5_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3348_RS11075Primary locus identifier stored in the genes table.
Old locus tagC3348_11075Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026594.1Sequence record reported by the local genomic context database.
Genomic interval2 291 509-2 292 786 nt1 278 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 291 509-2 293 438 ntGCF_002945755::NZ_CP026594.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945755::NZ_CP026594.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026594.1All displayed genes belong to this local TCS context.
Neighborhood span2 291 509-2 293 438 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 291 509 nt2 293 438 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3348_RS11075GCF_002945755#C3348_RS11075
HKClassicCurrent focus

2 291 509-2 292 786 nt · Reverse (-)

Old locus C3348_11075RefSeq WP_009890242.1
C3348_RS11080GCF_002945755#C3348_RS11080
RROmpR

2 292 770-2 293 438 nt · Reverse (-)

Old locus C3348_11080RefSeq WP_003424455.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2215984Run 6 · HK · 335 sequences
Representative sequenceGCF_000003215#QAC_RS0210660Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2215984

Simplified PFAM architecture for HKOC_2215984

PFAM domain coverage: 179 / 425 aa (42.1%)

1 aa425 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-422 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-422]
  • Domain count: 2
  • Matched identifier: HKOC_2215984
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0210660

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945755
AssemblyASM294575v1 · Complete Genomehaploid
Genome composition4 177 956 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key