Gene detail

C3348_RS03635

Histidine kinase, Classic

Clostridioides difficile · GCF_002945755

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945755#C3348_RS03635Stable P2CS identifier used across views.
GenomeGCF_002945755Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2881984Run 6 · 346 sequences · id 100% · cov 80%
External referencesWP_009892713.1 · A0A0H3N0D4 · MIST4 C3348_RS03635RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for C3348_RS03635
Domain-by-domain annotation2 items
1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw tokenHisKA:85:0.000000000000941:154:70:64
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw tokenHATPase_c:201:8.37e-28:304:106:109
  • Raw architecture: HisKA:85:0.000000000000941:154:70:64#HATPase_c:201:8.37e-28:304:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945755::NZ_CP026594.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span698753-700359Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3348_03635RefSeq proteinWP_009892713.1
Context group IDGCF_002945755::NZ_CP026594.1::G00013
Context members
C3348_RS03630C3348_RS03635
Partner locus tags
C3348_RS03630C3348_RS03635
Partner old locus tags
C3348_03630C3348_03635
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009892713.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N0D4Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N0D4_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3348_RS03635Primary locus identifier stored in the genes table.
Old locus tagC3348_03635Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026594.1Sequence record reported by the local genomic context database.
Genomic interval699 442-700 359 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span698 753-700 359 ntGCF_002945755::NZ_CP026594.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945755::NZ_CP026594.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026594.1All displayed genes belong to this local TCS context.
Neighborhood span698 753-700 359 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
698 753 nt700 359 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3348_RS03630GCF_002945755#C3348_RS03630
RROmpR

698 753-699 442 nt · Forward (+)

Old locus C3348_03630RefSeq WP_009888424.1
C3348_RS03635GCF_002945755#C3348_RS03635
HKClassicCurrent focus

699 442-700 359 nt · Forward (+)

Old locus C3348_03635RefSeq WP_009892713.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2881984Run 6 · HK · 346 sequences
Representative sequenceGCF_000003215#QAC_RS0203320Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2881984

Simplified PFAM architecture for HKOC_2881984

PFAM domain coverage: 171 / 305 aa (56.1%)

1 aa305 aa
HisKA: 88-154 aaHisKAHATPase_c: 201-304 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-154] | HATPase_c[201-304]
  • Domain count: 2
  • Matched identifier: HKOC_2881984
  • Positioned domains: HisKA 88-154 ; HATPase_c 201-304
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0203320

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 346 total members. Page 1 / 7.

GCF_000003215#QAC_RS0203320 (representative)
QAC_RS0203320 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000027105#CDR20291_RS03360
CDR20291_RS03360 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000085225#CD196_RS03495
CD196_RS03495 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000154645#UAA_RS0205195
UAA_RS0205195 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000154665#QAD_RS0203555
QAD_RS0203555 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000154685#AEC_RS0204790
AEC_RS0204790 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000155045#EAA_RS0203255
EAA_RS0203255 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000210455#CD7855_RS03355
CD7855_RS03355 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000211235#CDBI1_RS03450
CDBI1_RS03450 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000450765#QO5_RS03930
QO5_RS03930 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000451065#QSC_RS03195
QSC_RS03195 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000451785#QSO_RS03210
QSO_RS03210 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000451885#QU5_RS03255
QU5_RS03255 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000531785#BN176_RS03310
BN176_RS03310 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_000826625#BN2378_RS11950
BN2378_RS11950 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_001484885#CD26A54R_RS03320
CD26A54R_RS03320 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_001484895#CD26A54S_RS03390
CD26A54S_RS03390 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_001857645#HMPREF3082_RS03975
HMPREF3082_RS03975 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_001971835#BER28_RS03660
BER28_RS03660 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_001972015#BER29_RS03620
BER29_RS03620 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002301165#BGU11_RS04530
BGU11_RS04530 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002301945#BGU80_RS06600
BGU80_RS06600 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002302765#BGV01_RS15920
BGV01_RS15920 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002303165#BGV24_RS12455
BGV24_RS12455 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002335485#NCKUH21_RS03185
NCKUH21_RS03185 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002812585#CWR57_RS02955
CWR57_RS02955 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002891615#AMR88_RS01960
AMR88_RS01960 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002945415#C3W74_RS03630
C3W74_RS03630 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002945515#C3L34_RS03630
C3L34_RS03630 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002945665#C3347_RS03635
C3347_RS03635 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002945755#C3348_RS03635
C3348_RS03635 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002945855#C3350_RS03645
C3350_RS03645 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002945945#C3349_RS03635
C3349_RS03635 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002946035#C3351_RS03640
C3351_RS03640 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002946135#C3352_RS03645
C3352_RS03645 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002946195#C3353_RS03635
C3353_RS03635 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002954285#AMR92_RS06755
AMR92_RS06755 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_002954305#AMR91_RS11380
AMR91_RS11380 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003313545#CDIF27638_RS03640
CDIF27638_RS03640 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003313585#CDIF27640_RS03630
CDIF27640_RS03630 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003482035#CDIF28196_RS03630
CDIF28196_RS03630 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003597795#DA426_RS16270
DA426_RS16270 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003597815#DA430_RS03635
DA430_RS03635 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003597835#DA432_RS03575
DA432_RS03575 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003597895#DA422_RS03635
DA422_RS03635 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003597915#DA436_RS03570
DA436_RS03570 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003625415#C0215_RS15375
C0215_RS15375 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003625425#C0983_RS11985
C0983_RS11985 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003625435#C0984_RS15270
C0984_RS15270 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4
GCF_003862685#EGM06_RS10190
EGM06_RS10190 · HK · Classic
RefSeq: WP_009892713.1
UniProt: A0A0H3N0D4

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945755
AssemblyASM294575v1 · Complete Genomehaploid
Genome composition4 177 956 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key