Gene detail

C3W74_RS06545

Histidine kinase, Classic

Clostridioides difficile · GCF_002945415

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945415#C3W74_RS06545Stable P2CS identifier used across views.
GenomeGCF_002945415Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557601Run 6 · 352 sequences · id 100% · cov 80%
External referencesWP_009889050.1 · A0AB74QZK6 · MIST4 C3W74_RS06545RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage149 / 386 aa (38.6%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for C3W74_RS06545
Domain-by-domain annotation2 items
1 HisKA_3#1
187-250 aa · 64 aa · 16.6% of protein
Raw tokenHisKA_3:187:9.36e-20:250:65:68
2 HATPase_c#2
293-377 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:293:0.00000000000129:377:104:109
  • Raw architecture: HisKA_3:187:9.36e-20:250:65:68#HATPase_c:293:0.00000000000129:377:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945415::NZ_CP026592.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1345524-1347321Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3W74_06545RefSeq proteinWP_009889050.1
Context group IDGCF_002945415::NZ_CP026592.1::G00020
Context members
C3W74_RS06540C3W74_RS06545
Partner locus tags
C3W74_RS06540C3W74_RS06545
Partner old locus tags
C3W74_06540C3W74_06545
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889050.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QZK6Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QZK6_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3W74_RS06545Primary locus identifier stored in the genes table.
Old locus tagC3W74_06545Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026592.1Sequence record reported by the local genomic context database.
Genomic interval1 346 161-1 347 321 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 345 524-1 347 321 ntGCF_002945415::NZ_CP026592.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945415::NZ_CP026592.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026592.1All displayed genes belong to this local TCS context.
Neighborhood span1 345 524-1 347 321 nt1 798 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 345 524 nt1 347 321 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3W74_RS06540GCF_002945415#C3W74_RS06540
RRNarL

1 345 524-1 346 168 nt · Reverse (-)

Old locus C3W74_06540RefSeq WP_009889048.1
C3W74_RS06545GCF_002945415#C3W74_RS06545
HKClassicCurrent focus

1 346 161-1 347 321 nt · Reverse (-)

Old locus C3W74_06545RefSeq WP_009889050.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557601Run 6 · HK · 352 sequences
Representative sequenceGCF_000003215#QAC_RS0206170Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557601

Simplified PFAM architecture for HKOC_2557601

PFAM domain coverage: 149 / 386 aa (38.6%)

1 aa386 aa
HisKA_3: 187-250 aaHisKA_3HATPase_c: 293-377 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[187-250] | HATPase_c[293-377]
  • Domain count: 2
  • Matched identifier: HKOC_2557601
  • Positioned domains: HisKA_3 187-250 ; HATPase_c 293-377
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0206170

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945415
AssemblyASM294541v1 · Complete Genomehaploid
Genome composition4 119 484 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key