Gene detail

C3W74_RS03785

Histidine kinase, Classic

Clostridioides difficile · GCF_002945415

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945415#C3W74_RS03785Stable P2CS identifier used across views.
GenomeGCF_002945415Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1737534Run 6 · 343 sequences · id 100% · cov 80%
External referencesWP_009892732.1 · A0A0H3MZP2 · MIST4 C3W74_RS03785RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for C3W74_RS03785
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.0000000000019:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:1.68e-17:466:111:109
  • Raw architecture: HisKA:245:0.0000000000019:309:65:64#HATPase_c:357:1.68e-17:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945415::NZ_CP026592.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span743438-745596Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3W74_03785RefSeq proteinWP_009892732.1
Context group IDGCF_002945415::NZ_CP026592.1::G00014
Context members
C3W74_RS03780C3W74_RS03785
Partner locus tags
C3W74_RS03780C3W74_RS03785
Partner old locus tags
C3W74_03780C3W74_03785
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009892732.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZP2Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZP2_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3W74_RS03785Primary locus identifier stored in the genes table.
Old locus tagC3W74_03785Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026592.1Sequence record reported by the local genomic context database.
Genomic interval744 190-745 596 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span743 438-745 596 ntGCF_002945415::NZ_CP026592.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945415::NZ_CP026592.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026592.1All displayed genes belong to this local TCS context.
Neighborhood span743 438-745 596 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
743 438 nt745 596 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3W74_RS03780GCF_002945415#C3W74_RS03780
RROmpR

743 438-744 145 nt · Forward (+)

Old locus C3W74_03780RefSeq WP_009888460.1
C3W74_RS03785GCF_002945415#C3W74_RS03785
HKClassicCurrent focus

744 190-745 596 nt · Forward (+)

Old locus C3W74_03785RefSeq WP_009892732.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1737534Run 6 · HK · 343 sequences
Representative sequenceGCF_000003215#QAC_RS0203465Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1737534

Simplified PFAM architecture for HKOC_1737534

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1737534
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0203465

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 343 total members. Page 1 / 7.

GCF_000003215#QAC_RS0203465 (representative)
QAC_RS0203465 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000027105#CDR20291_RS03505
CDR20291_RS03505 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000085225#CD196_RS03645
CD196_RS03645 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000154645#UAA_RS0205340
UAA_RS0205340 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000154665#QAD_RS0203700
QAD_RS0203700 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000154685#AEC_RS0204935
AEC_RS0204935 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000155045#EAA_RS0203400
EAA_RS0203400 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000210455#CD7855_RS03500
CD7855_RS03500 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000211235#CDBI1_RS03590
CDBI1_RS03590 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000450765#QO5_RS04085
QO5_RS04085 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000451065#QSC_RS03345
QSC_RS03345 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000451785#QSO_RS03360
QSO_RS03360 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000451885#QU5_RS03405
QU5_RS03405 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_000826625#BN2378_RS12100
BN2378_RS12100 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_001484885#CD26A54R_RS03470
CD26A54R_RS03470 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_001484895#CD26A54S_RS03540
CD26A54S_RS03540 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_001857645#HMPREF3082_RS07840
HMPREF3082_RS07840 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_001971835#BER28_RS03815
BER28_RS03815 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_001972015#BER29_RS03775
BER29_RS03775 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002301945#BGU80_RS06755
BGU80_RS06755 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002302765#BGV01_RS17570
BGV01_RS17570 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002303165#BGV24_RS13505
BGV24_RS13505 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002335485#NCKUH21_RS03340
NCKUH21_RS03340 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002812585#CWR57_RS03110
CWR57_RS03110 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002945415#C3W74_RS03785
C3W74_RS03785 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002945515#C3L34_RS03785
C3L34_RS03785 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002945665#C3347_RS03790
C3347_RS03790 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002945755#C3348_RS03790
C3348_RS03790 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002945855#C3350_RS03800
C3350_RS03800 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002945945#C3349_RS03790
C3349_RS03790 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002946035#C3351_RS03795
C3351_RS03795 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002946135#C3352_RS03800
C3352_RS03800 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002946195#C3353_RS03790
C3353_RS03790 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002954285#AMR92_RS06915
AMR92_RS06915 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_002954305#AMR91_RS11225
AMR91_RS11225 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003313545#CDIF27638_RS03795
CDIF27638_RS03795 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003313585#CDIF27640_RS03785
CDIF27640_RS03785 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003482035#CDIF28196_RS03785
CDIF28196_RS03785 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003597795#DA426_RS16115
DA426_RS16115 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003597815#DA430_RS03790
DA430_RS03790 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003597835#DA432_RS03730
DA432_RS03730 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003597895#DA422_RS03790
DA422_RS03790 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003597915#DA436_RS03725
DA436_RS03725 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003625415#C0215_RS10905
C0215_RS10905 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003625425#C0983_RS18730
C0983_RS18730 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003625435#C0984_RS11040
C0984_RS11040 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003862685#EGM06_RS10040
EGM06_RS10040 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003863035#EGL82_RS09985
EGL82_RS09985 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003863055#EGM11_RS09535
EGM11_RS09535 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2
GCF_003863075#EGL79_RS09210
EGL79_RS09210 · HK · Classic
RefSeq: WP_009892732.1
UniProt: A0A0H3MZP2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945415
AssemblyASM294541v1 · Complete Genomehaploid
Genome composition4 119 484 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key