Gene detail

AWN78_RS00205

Histidine kinase, Classic

Clostridioides difficile · GCF_002940905

ClassHKTypeClassicLength462 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_002940905#AWN78_RS00205Stable P2CS identifier used across views.
GenomeGCF_002940905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1807357Run 6 · 143 sequences · id 100% · cov 80%
External referencesWP_011861185.1 · Q18BL5 · MIST4 AWN78_RS00205RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length462 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 462 aa (37.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa462 aa
HisKA: 241-305 aa (65 aa)1HATPase_c: 352-460 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
241-305 aa · 65 aa · 14.1% of protein
Raw tokenHisKA:241:0.00000000000123:305:65:64
2 HATPase_c#2
352-460 aa · 109 aa · 23.6% of protein
Raw tokenHATPase_c:352:3.94e-21:460:109:109
  • Raw architecture: HisKA:241:0.00000000000123:305:65:64#HATPase_c:352:3.94e-21:460:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_002940905::NZ_LRDI01000001.1::G00001
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span44739-46127Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAWN78_00205RefSeq proteinWP_011861185.1
Context group IDGCF_002940905::NZ_LRDI01000001.1::G00001
Context members
AWN78_RS00205
Partner locus tags
AWN78_RS00205
Partner old locus tags
AWN78_00205
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011861185.1Primary protein accession used for annex mappings.
UniProt accessionQ18BL5Primary UniProt accession resolved in the annex database.
UniProt IDQ18BL5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAWN78_RS00205Primary locus identifier stored in the genes table.
Old locus tagAWN78_00205Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LRDI01000001.1Sequence record reported by the local genomic context database.
Genomic interval44 739-46 127 nt1 389 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span44 739-46 127 ntGCF_002940905::NZ_LRDI01000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002940905::NZ_LRDI01000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LRDI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span44 739-46 127 nt1 389 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
44 739 nt46 127 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

AWN78_RS00205GCF_002940905#AWN78_RS00205
HKClassicCurrent focus

44 739-46 127 nt · Forward (+)

Old locus AWN78_00205RefSeq WP_011861185.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1807357Run 6 · HK · 143 sequences
Representative sequenceGCF_000009205#CD630_RS07470Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1807357

Simplified PFAM architecture for HKOC_1807357

PFAM domain coverage: 174 / 462 aa (37.7%)

1 aa462 aa
HisKA: 241-305 aaHisKAHATPase_c: 352-460 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[241-305] | HATPase_c[352-460]
  • Domain count: 2
  • Matched identifier: HKOC_1807357
  • Positioned domains: HisKA 241-305 ; HATPase_c 352-460
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS07470

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 143 total members. Page 1 / 3.

GCF_000009205#CD630_RS07470 (representative)
CD630_RS07470 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000448885#QAU_RS06505
QAU_RS06505 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000451185#QQ3_RS07050
QQ3_RS07050 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000451745#QSK_RS06515
QSK_RS06515 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000530595#BN185_RS06835
BN185_RS06835 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000531225#BN184_RS07215
BN184_RS07215 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000531385#BN169_RS08545
BN169_RS08545 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000531715#BN191_RS05985
BN191_RS05985 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000828225#SE46_RS07040
SE46_RS07040 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000828235#SE44_RS08935
SE44_RS08935 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000828255#SE45_RS07755
SE45_RS07755 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000828325#NX98_RS09085
NX98_RS09085 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000932055#CDIF630_RS07635
CDIF630_RS07635 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_000953275#CD630DERM_RS07615
CD630DERM_RS07615 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002080065#CDIF630erm_RS07750
CDIF630erm_RS07750 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002082945#A6J96_RS07240
A6J96_RS07240 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002082985#A6J97_RS19940
A6J97_RS19940 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002302085#BGU87_RS09255
BGU87_RS09255 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002303415#BGU61_RS04255
BGU61_RS04255 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002303575#BGU68_RS00820
BGU68_RS00820 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002303575#BGU68_RS01305
BGU68_RS01305 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002303695#BGU74_RS05115
BGU74_RS05115 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_002940905#AWN78_RS00205
AWN78_RS00205 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_003313565#CDIF27639_RS07075
CDIF27639_RS07075 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_003327305#DVB08_RS08830
DVB08_RS08830 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_003482035#CDIF28196_RS06960
CDIF28196_RS06960 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_003932635#EGL77_RS13635
EGL77_RS13635 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_004313765#E0N69_RS13895
E0N69_RS13895 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_004313965#E0N81_RS05910
E0N81_RS05910 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_004313985#E0N77_RS01670
E0N77_RS01670 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_004314885#E0O59_RS08365
E0O59_RS08365 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_004316085#E0P76_RS02825
E0P76_RS02825 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_004316465#E0P94_RS16040
E0P94_RS16040 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_006408335#DA411_RS07605
DA411_RS07605 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_018884885#E1H32_RS06950
E1H32_RS06950 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_018884965#E1H29_RS07120
E1H29_RS07120 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_019427245#K1N47_RS16520
K1N47_RS16520 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_022342355#C1S62_RS14165
C1S62_RS14165 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_022342465#C1M58_RS02695
C1M58_RS02695 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_022695655#LWC40_RS06870
LWC40_RS06870 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_024451525#NOL94_RS10305
NOL94_RS10305 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_024628745#NQ182_RS20035
NQ182_RS20035 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_025532245#J4G21_RS19925
J4G21_RS19925 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_025532285#J4G20_RS15075
J4G20_RS15075 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_025532335#J4G22_RS18260
J4G22_RS18260 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_025532705#H3U13_RS10395
H3U13_RS10395 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_025532755#H3U05_RS11465
H3U05_RS11465 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_025532775#H3U11_RS11425
H3U11_RS11425 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_025532885#H3U12_RS13245
H3U12_RS13245 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5
GCF_025532975#H3U14_RS09995
H3U14_RS09995 · HK · Classic
RefSeq: WP_011861185.1
UniProt: Q18BL5

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002940905
AssemblyASM294090v1 · Contighaploid
Genome composition4 212 322 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 50 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key