Gene detail

AWN80_RS12570

Histidine kinase, Classic

Clostridioides difficile · GCF_002940865

ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002940865#AWN80_RS12570Stable P2CS identifier used across views.
GenomeGCF_002940865Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2857949Run 6 · 119 sequences · id 100% · cov 80%
External referencesWP_009898775.1 · MIST4 AWN80_RS12570RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for AWN80_RS12570
Domain-by-domain annotation2 items
1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw tokenHisKA:117:0.000000000191:177:61:64
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw tokenHATPase_c:222:6.89e-24:328:107:109
  • Raw architecture: HisKA:117:0.000000000191:177:61:64#HATPase_c:222:6.89e-24:328:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002940865::NZ_LRDJ01000167.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span691-2353Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAWN80_14770RefSeq proteinWP_009898775.1
Context group IDGCF_002940865::NZ_LRDJ01000167.1::G00040
Context members
AWN80_RS12565AWN80_RS12570
Partner locus tags
AWN80_RS12565AWN80_RS12570
Partner old locus tags
AWN80_14765AWN80_14770
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009898775.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAWN80_RS12570Primary locus identifier stored in the genes table.
Old locus tagAWN80_14770Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LRDJ01000167.1Sequence record reported by the local genomic context database.
Genomic interval1 364-2 353 nt990 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span691-2 353 ntGCF_002940865::NZ_LRDJ01000167.1::G00040

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002940865::NZ_LRDJ01000167.1::G00040

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LRDJ01000167.1All displayed genes belong to this local TCS context.
Neighborhood span691-2 353 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
691 nt2 353 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

AWN80_RS12565GCF_002940865#AWN80_RS12565
RROmpR

691-1 377 nt · Forward (+)

Old locus AWN80_14765RefSeq WP_003434895.1
AWN80_RS12570GCF_002940865#AWN80_RS12570
HKClassicCurrent focus

1 364-2 353 nt · Forward (+)

Old locus AWN80_14770RefSeq WP_009898775.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2857949Run 6 · HK · 119 sequences
Representative sequenceGCF_000154625#QAB_RS0220635Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2857949

Simplified PFAM architecture for HKOC_2857949

PFAM domain coverage: 169 / 329 aa (51.4%)

1 aa329 aa
HisKA: 116-177 aaHisKAHATPase_c: 222-328 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[116-177] | HATPase_c[222-328]
  • Domain count: 2
  • Matched identifier: HKOC_2857949
  • Positioned domains: HisKA 116-177 ; HATPase_c 222-328
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0220635

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002940865
AssemblyASM294086v1 · Contighaploid
Genome composition4 126 808 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 44 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key