Gene detail

AWN77_RS17825

Histidine kinase, Classic

Clostridioides difficile · GCF_002940825

ClassHKTypeClassicLength334 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002940825#AWN77_RS17825Stable P2CS identifier used across views.
GenomeGCF_002940825Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2849778Run 6 · 262 sequences · id 100% · cov 80%
External referencesWP_003429756.1 · A0A9P3TWR4 · MIST4 AWN77_RS17825RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length334 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage169 / 334 aa (50.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa334 aa
HisKA: 118-178 aa (61 aa)1HATPase_c: 224-331 aa (108 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
118-178 aa · 61 aa · 18.3% of protein
Raw tokenHisKA:118:0.00000959:178:63:64
2 HATPase_c#2
224-331 aa · 108 aa · 32.3% of protein
Raw tokenHATPase_c:224:2.09e-25:331:108:109
  • Raw architecture: HisKA:118:0.00000959:178:63:64#HATPase_c:224:2.09e-25:331:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002940825::NZ_LRDM01000191.1::G00049
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6295-7997Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAWN77_18750RefSeq proteinWP_003429756.1
Context group IDGCF_002940825::NZ_LRDM01000191.1::G00049
Context members
AWN77_RS17825AWN77_RS17830
Partner locus tags
AWN77_RS17825AWN77_RS17830
Partner old locus tags
AWN77_18750AWN77_18755
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003429756.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3TWR4Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3TWR4_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAWN77_RS17825Primary locus identifier stored in the genes table.
Old locus tagAWN77_18750Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LRDM01000191.1Sequence record reported by the local genomic context database.
Genomic interval6 295-7 299 nt1 005 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span6 295-7 997 ntGCF_002940825::NZ_LRDM01000191.1::G00049

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002940825::NZ_LRDM01000191.1::G00049

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LRDM01000191.1All displayed genes belong to this local TCS context.
Neighborhood span6 295-7 997 nt1 703 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 295 nt7 997 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

AWN77_RS17825GCF_002940825#AWN77_RS17825
HKClassicCurrent focus

6 295-7 299 nt · Reverse (-)

Old locus AWN77_18750RefSeq WP_003429756.1
AWN77_RS17830GCF_002940825#AWN77_RS17830
RROmpR

7 323-7 997 nt · Reverse (-)

Old locus AWN77_18755RefSeq WP_003429757.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2849778Run 6 · HK · 262 sequences
Representative sequenceGCF_000210395#CDM68_RS07690Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2849778

Simplified PFAM architecture for HKOC_2849778

PFAM domain coverage: 108 / 334 aa (32.3%)

1 aa334 aa
HATPase_c: 224-331 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[224-331]
  • Domain count: 1
  • Matched identifier: HKOC_2849778
  • Positioned domains: HATPase_c 224-331
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS07690

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002940825
AssemblyASM294082v1 · Contighaploid
Genome composition4 390 681 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key