Gene detail

AWN77_RS07025

Histidine kinase, Classic

Clostridioides difficile · GCF_002940825

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_002940825#AWN77_RS07025Stable P2CS identifier used across views.
GenomeGCF_002940825Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0387834Run 6 · 216 sequences · id 100% · cov 80%
External referencesWP_003430988.1 · A0A9P3TTT4 · MIST4 AWN77_RS07025RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PASHisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage295 / 912 aa (32.3%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
PAS: 521-632 aa (112 aa)1HisKA: 655-726 aa (72 aa)2HATPase_c: 773-883 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS#1
521-632 aa · 112 aa · 12.3% of protein
Raw tokenPAS:521:0.0000425:632:114:113
2 HisKA#2
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.00000000000000745:726:72:64
3 HATPase_c#3
773-883 aa · 111 aa · 12.2% of protein
Raw tokenHATPase_c:773:3.97e-31:883:111:109
  • Raw architecture: PAS:521:0.0000425:632:114:113#HisKA:655:0.00000000000000745:726:72:64#HATPase_c:773:3.97e-31:883:111:109
  • Domain description: 1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_002940825::NZ_LRDM01000098.1::G00022
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span229630-232368Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAWN77_02260RefSeq proteinWP_003430988.1
Context group IDGCF_002940825::NZ_LRDM01000098.1::G00022
Context members
AWN77_RS07025
Partner locus tags
AWN77_RS07025
Partner old locus tags
AWN77_02260
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003430988.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3TTT4Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3TTT4_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAWN77_RS07025Primary locus identifier stored in the genes table.
Old locus tagAWN77_02260Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LRDM01000098.1Sequence record reported by the local genomic context database.
Genomic interval229 630-232 368 nt2 739 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span229 630-232 368 ntGCF_002940825::NZ_LRDM01000098.1::G00022

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002940825::NZ_LRDM01000098.1::G00022

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LRDM01000098.1All displayed genes belong to this local TCS context.
Neighborhood span229 630-232 368 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
229 630 nt232 368 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

AWN77_RS07025GCF_002940825#AWN77_RS07025
HKClassicCurrent focus

229 630-232 368 nt · Reverse (-)

Old locus AWN77_02260RefSeq WP_003430988.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0387834Run 6 · HK · 216 sequences
Representative sequenceGCF_000210395#CDM68_RS12810Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + PAS_9 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0387834

Simplified PFAM architecture for HKOC_0387834

PFAM domain coverage: 340 / 912 aa (37.3%)

1 aa912 aa
PAS_8: 303-355 aaPAS_8PAS_9: 529-632 aaPAS_9HisKA: 655-726 aaHisKAHATPase_c: 773-883 aaHATPase_c
PAS_8PAS_9HisKAHATPase_c
  • Simplified architecture: PAS_8 + PAS_9 + HisKA + HATPase_c
  • Raw architecture: PAS_8[303-355] | PAS_9[529-632] | HisKA[655-726] | HATPase_c[773-883]
  • Domain count: 4
  • Matched identifier: HKOC_0387834
  • Positioned domains: PAS_8 303-355 ; PAS_9 529-632 ; HisKA 655-726 ; HATPase_c 773-883
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS12810

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 216 total members. Page 1 / 5.

GCF_000210395#CDM68_RS12810 (representative)
CDM68_RS12810 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_000210415#CDCF5_RS12760
CDCF5_RS12760 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_000235825#HMPREF1122_RS00580
HMPREF1122_RS00580 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_000235925#HMPREF1123_RS08245
HMPREF1123_RS08245 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_000449945#QIG_RS12345
QIG_RS12345 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_000452125#QUY_RS12630
QUY_RS12630 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_000452165#QW3_RS12870
QW3_RS12870 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_000530915#BN167_RS12895
BN167_RS12895 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_000531625#BN168_RS11370
BN168_RS11370 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_001971875#BER36_RS13495
BER36_RS13495 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_001972195#BER37_RS13135
BER37_RS13135 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_002301085#BGU06_RS05345
BGU06_RS05345 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_002301435#BGU22_RS04635
BGU22_RS04635 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_002301555#BGU29_RS00985
BGU29_RS00985 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_002301635#BGU36_RS02720
BGU36_RS02720 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_002303545#BGU67_RS09145
BGU67_RS09145 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_002940825#AWN77_RS07025
AWN77_RS07025 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003095675#DDG63_RS13235
DDG63_RS13235 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003095695#DDG61_RS13655
DDG61_RS13655 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003324015#DVA89_RS01370
DVA89_RS01370 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003324025#DVA88_RS03115
DVA88_RS03115 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003324035#DVA87_RS01935
DVA87_RS01935 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003326835#DVA92_RS04920
DVA92_RS04920 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003326845#DVA91_RS01505
DVA91_RS01505 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003326885#DVA93_RS04915
DVA93_RS04915 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003326915#DVA96_RS04070
DVA96_RS04070 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003326935#DVA97_RS01575
DVA97_RS01575 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003326945#DVA98_RS05185
DVA98_RS05185 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003326985#DVB00_RS05935
DVB00_RS05935 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327015#DVB04_RS02315
DVB04_RS02315 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327025#DVB06_RS01635
DVB06_RS01635 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327055#DVB02_RS01985
DVB02_RS01985 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327065#DVB01_RS01800
DVB01_RS01800 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327105#DVB12_RS01990
DVB12_RS01990 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327145#DVB10_RS03695
DVB10_RS03695 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327165#DVB07_RS02205
DVB07_RS02205 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327185#DVB14_RS03810
DVB14_RS03810 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327205#DVB16_RS09060
DVB16_RS09060 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327215#DVB15_RS01785
DVB15_RS01785 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327245#DVB19_RS00920
DVB19_RS00920 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327265#DVB18_RS03115
DVB18_RS03115 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327325#DVB05_RS00605
DVB05_RS00605 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327345#DVB13_RS01395
DVB13_RS01395 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327365#DVB11_RS06980
DVB11_RS06980 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003327755#DVB17_RS01640
DVB17_RS01640 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003328455#DR993_RS07000
DR993_RS07000 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003482225#CDIF28670_RS13915
CDIF28670_RS13915 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_003482255#CDIF29627_RS13270
CDIF29627_RS13270 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_004313745#E0N65_RS03940
E0N65_RS03940 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4
GCF_004313785#E0N66_RS02195
E0N66_RS02195 · HK · Classic
RefSeq: WP_003430988.1
UniProt: A0A9P3TTT4

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002940825
AssemblyASM294082v1 · Contighaploid
Genome composition4 390 681 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key